Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats

The present study aimed to investigate the effects of fortification and nano-size reduction on absorption and bioavailability of calcium from the fortified milk in ovariectomized (OVX) and OVX-osteoporosis rats. The main goal was to determine the effect of daily consumption of experimental diets on...

Full description

Bibliographic Details
Main Authors: Erfanian, Arezoo, Mirhosseini, Hamed, Abd Manap, Mohd Yazid, Rasti, Babak, Bejo, Mohd Hair
Format: Article
Published: Elsevier 2014
_version_ 1796972455316684800
author Erfanian, Arezoo
Mirhosseini, Hamed
Abd Manap, Mohd Yazid
Rasti, Babak
Bejo, Mohd Hair
author_facet Erfanian, Arezoo
Mirhosseini, Hamed
Abd Manap, Mohd Yazid
Rasti, Babak
Bejo, Mohd Hair
author_sort Erfanian, Arezoo
collection UPM
description The present study aimed to investigate the effects of fortification and nano-size reduction on absorption and bioavailability of calcium from the fortified milk in ovariectomized (OVX) and OVX-osteoporosis rats. The main goal was to determine the effect of daily consumption of experimental diets on serum calcium, feces calcium, bone calcium, bone breaking strength and bone morphology among rats. This study was conducted to optimize the preparation of nano-fortified milk powder. Then, the calcium bioavailability in 64 female OVX rats and OVX-osteoporosis rats was investigated. The results revealed that bone breaking strength (maximum load) and bone calcium increased with consumption of nano-fortified diet compared with fortified diet. The same observations were seen for bone morphology. OVX rats exhibited higher calcium bioavailability and absorption than OVX-osteoporosis rats with regard to fortified and nano-fortified diets. The amount of calcium absorption from fortified and nano-fortified milk powders in OVX rats was 63.54% and 89.06%, respectively. The bioavailability of calcium from fortified and nano-fortified milk powders in OVX rats was 24.64% and 41.65%, respectively. Moreover, the calcium bioavailability (%) from fortified and nano-fortified milk powders in OVX-osteoporosis rats was 9.74% and 30.17%, respectively. In OVX-osteoporosis group, the absorption levels of calcium from the same experimental diets were 60.54% and 89.09%, respectively.
first_indexed 2024-03-06T08:28:16Z
format Article
id upm.eprints-34193
institution Universiti Putra Malaysia
last_indexed 2024-03-06T08:28:16Z
publishDate 2014
publisher Elsevier
record_format dspace
spelling upm.eprints-341932015-12-09T01:08:07Z http://psasir.upm.edu.my/id/eprint/34193/ Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats Erfanian, Arezoo Mirhosseini, Hamed Abd Manap, Mohd Yazid Rasti, Babak Bejo, Mohd Hair The present study aimed to investigate the effects of fortification and nano-size reduction on absorption and bioavailability of calcium from the fortified milk in ovariectomized (OVX) and OVX-osteoporosis rats. The main goal was to determine the effect of daily consumption of experimental diets on serum calcium, feces calcium, bone calcium, bone breaking strength and bone morphology among rats. This study was conducted to optimize the preparation of nano-fortified milk powder. Then, the calcium bioavailability in 64 female OVX rats and OVX-osteoporosis rats was investigated. The results revealed that bone breaking strength (maximum load) and bone calcium increased with consumption of nano-fortified diet compared with fortified diet. The same observations were seen for bone morphology. OVX rats exhibited higher calcium bioavailability and absorption than OVX-osteoporosis rats with regard to fortified and nano-fortified diets. The amount of calcium absorption from fortified and nano-fortified milk powders in OVX rats was 63.54% and 89.06%, respectively. The bioavailability of calcium from fortified and nano-fortified milk powders in OVX rats was 24.64% and 41.65%, respectively. Moreover, the calcium bioavailability (%) from fortified and nano-fortified milk powders in OVX-osteoporosis rats was 9.74% and 30.17%, respectively. In OVX-osteoporosis group, the absorption levels of calcium from the same experimental diets were 60.54% and 89.09%, respectively. Elsevier 2014-12 Article PeerReviewed Erfanian, Arezoo and Mirhosseini, Hamed and Abd Manap, Mohd Yazid and Rasti, Babak and Bejo, Mohd Hair (2014) Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats. Food Research International, 66. pp. 1-11. ISSN 0963-9969; ESSN: 1873-7145 http://www.sciencedirect.com/science/article/pii/S096399691400564X 10.1016/j.foodres.2014.08.026
spellingShingle Erfanian, Arezoo
Mirhosseini, Hamed
Abd Manap, Mohd Yazid
Rasti, Babak
Bejo, Mohd Hair
Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title_full Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title_fullStr Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title_full_unstemmed Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title_short Influence of nano-size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
title_sort influence of nano size reduction on absorption and bioavailability of calcium from fortified milk powder in rats
work_keys_str_mv AT erfanianarezoo influenceofnanosizereductiononabsorptionandbioavailabilityofcalciumfromfortifiedmilkpowderinrats
AT mirhosseinihamed influenceofnanosizereductiononabsorptionandbioavailabilityofcalciumfromfortifiedmilkpowderinrats
AT abdmanapmohdyazid influenceofnanosizereductiononabsorptionandbioavailabilityofcalciumfromfortifiedmilkpowderinrats
AT rastibabak influenceofnanosizereductiononabsorptionandbioavailabilityofcalciumfromfortifiedmilkpowderinrats
AT bejomohdhair influenceofnanosizereductiononabsorptionandbioavailabilityofcalciumfromfortifiedmilkpowderinrats