Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review

Nitrate is harmful to humans as it can form endogenous nitrosamines which can cause cancer. The major contribution of nitrate contamination in well water is largely from agricultural activities (e.g.; fertilizers and pesticide), wastewater treatment plant discharge, animal yard and manure storage la...

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Main Authors: Shamsuddin, Aida Soraya, Syed ismail, Sharifah Norkhadijah, Mohd. Sham, Shaharuddin, Zainal Abidin, Emilia
Format: Article
Language:English
Published: Global Society of Scientific Research and Researchers 2014
Online Access:http://psasir.upm.edu.my/id/eprint/34652/1/Nitrate%20in%20groundwater%20and%20excretion%20of%20nitrate%20and%20nitrosamines%20in%20urine.pdf
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author Shamsuddin, Aida Soraya
Syed ismail, Sharifah Norkhadijah
Mohd. Sham, Shaharuddin
Zainal Abidin, Emilia
author_facet Shamsuddin, Aida Soraya
Syed ismail, Sharifah Norkhadijah
Mohd. Sham, Shaharuddin
Zainal Abidin, Emilia
author_sort Shamsuddin, Aida Soraya
collection UPM
description Nitrate is harmful to humans as it can form endogenous nitrosamines which can cause cancer. The major contribution of nitrate contamination in well water is largely from agricultural activities (e.g.; fertilizers and pesticide), wastewater treatment plant discharge, animal yard and manure storage lagoons. Biomarkers such as urine and saliva can be used to determine the occurrence and formation of nitrosamines in the human body. This paper provides an overview of nitrate occurrence in groundwater and the mechanism of nitrosamines formation and its excretion from human body via urine and saliva. The suitability of urine and saliva as biomarkers of endogenous nitrosamines formation were also discussed in this review.
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spelling upm.eprints-346522016-01-27T02:18:36Z http://psasir.upm.edu.my/id/eprint/34652/ Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review Shamsuddin, Aida Soraya Syed ismail, Sharifah Norkhadijah Mohd. Sham, Shaharuddin Zainal Abidin, Emilia Nitrate is harmful to humans as it can form endogenous nitrosamines which can cause cancer. The major contribution of nitrate contamination in well water is largely from agricultural activities (e.g.; fertilizers and pesticide), wastewater treatment plant discharge, animal yard and manure storage lagoons. Biomarkers such as urine and saliva can be used to determine the occurrence and formation of nitrosamines in the human body. This paper provides an overview of nitrate occurrence in groundwater and the mechanism of nitrosamines formation and its excretion from human body via urine and saliva. The suitability of urine and saliva as biomarkers of endogenous nitrosamines formation were also discussed in this review. Global Society of Scientific Research and Researchers 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/34652/1/Nitrate%20in%20groundwater%20and%20excretion%20of%20nitrate%20and%20nitrosamines%20in%20urine.pdf Shamsuddin, Aida Soraya and Syed ismail, Sharifah Norkhadijah and Mohd. Sham, Shaharuddin and Zainal Abidin, Emilia (2014) Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review. International Journal of Sciences: Basic and Applied Research, 15 (2). pp. 176-191. ISSN 2307-4531 http://gssrr.org/index.php?journal=JournalOfBasicAndApplied&page=article&op=view&path[]=2946
spellingShingle Shamsuddin, Aida Soraya
Syed ismail, Sharifah Norkhadijah
Mohd. Sham, Shaharuddin
Zainal Abidin, Emilia
Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title_full Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title_fullStr Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title_full_unstemmed Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title_short Nitrate in groundwater and excretion of nitrate and nitrosamines in urine: a review
title_sort nitrate in groundwater and excretion of nitrate and nitrosamines in urine a review
url http://psasir.upm.edu.my/id/eprint/34652/1/Nitrate%20in%20groundwater%20and%20excretion%20of%20nitrate%20and%20nitrosamines%20in%20urine.pdf
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AT mohdshamshaharuddin nitrateingroundwaterandexcretionofnitrateandnitrosaminesinurineareview
AT zainalabidinemilia nitrateingroundwaterandexcretionofnitrateandnitrosaminesinurineareview