Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats
The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells agains...
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| Format: | Article |
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Hindawi Publishing Corporation
2014
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| author | Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah |
| author_facet | Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah |
| author_sort | Movahedi, Ariyo |
| collection | UPM |
| description | The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. |
| first_indexed | 2024-03-06T08:31:41Z |
| format | Article |
| id | upm.eprints-35222 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:31:41Z |
| publishDate | 2014 |
| publisher | Hindawi Publishing Corporation |
| record_format | dspace |
| spelling | upm.eprints-352222015-12-31T03:00:56Z http://psasir.upm.edu.my/id/eprint/35222/ Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah The term cancer has been concomitant with despair, agony, and dreadful death. Like many other diseases, herbal therapy has been used to prevent or suppress cancer. The present study investigated the capability of the decoction of Teucrium polium L. from Lamiaceae family to protect liver cells against hepatocellular carcinoma in carcinogenesis-induced animal model. After 28 weeks of treatment with decoction of Teucrium polium L., serum biochemical markers including ALT, AST, AFP, GGT, ALP, HCY, TNF-α, α2MG, and CBG have been regulated auspiciously. Total antioxidant status also has been increased intensely. Liver lesion score in treated group was lessened and glucocorticoid activity has been intensified significantly. In conclusion, Teucrium polium L. decoction might inhibit or suppress liver cancer development. Hindawi Publishing Corporation 2014 Article PeerReviewed Movahedi, Ariyo and Basir, Rusliza and Rahmat, Asmah and Charaffedine, Mohammad and Othman, Fauziah (2014) Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats. Evidence-Based Complementary and Alternative Medicine, 2014. art. no. 726724. pp. 1-9. ISSN 1741-427X; ESSN: 1741-4288 http://www.hindawi.com/journals/ecam/2014/726724/abs/ 10.1155/2014/726724 |
| spellingShingle | Movahedi, Ariyo Basir, Rusliza Rahmat, Asmah Charaffedine, Mohammad Othman, Fauziah Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title | Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title_full | Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title_fullStr | Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title_full_unstemmed | Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title_short | Remarkable anticancer activity of Teucrium polium on hepatocellular carcinogenic rats |
| title_sort | remarkable anticancer activity of teucrium polium on hepatocellular carcinogenic rats |
| work_keys_str_mv | AT movahediariyo remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT basirrusliza remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT rahmatasmah remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT charaffedinemohammad remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats AT othmanfauziah remarkableanticanceractivityofteucriumpoliumonhepatocellularcarcinogenicrats |