Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital
A case-control study was conducted based on medical cases of 100 hospitalized patients with Pseudomonas aeruginosa-isolation at a Malaysian hospital. Cases with 50 multidrug-resistant P. aeruginosa MDRPA and 50 non-multidrug-resistant P. aeruginosa (NMDRPA) were randomly included and compared with s...
| Main Authors: | , , , , , |
|---|---|
| Format: | Article |
| Published: |
Universiti Kebangsaan Malaysia Press
2015
|
| _version_ | 1825948615764344832 |
|---|---|
| author | Mohd Desa, Mohd Nasir M. H. , Nurnajwa Lay, J. Teoh, J. C. Amin Nordin, Syafinaz Mohd Taib, Niazlin |
| author_facet | Mohd Desa, Mohd Nasir M. H. , Nurnajwa Lay, J. Teoh, J. C. Amin Nordin, Syafinaz Mohd Taib, Niazlin |
| author_sort | Mohd Desa, Mohd Nasir |
| collection | UPM |
| description | A case-control study was conducted based on medical cases of 100 hospitalized patients with Pseudomonas aeruginosa-isolation at a Malaysian hospital. Cases with 50 multidrug-resistant P. aeruginosa MDRPA and 50 non-multidrug-resistant P. aeruginosa (NMDRPA) were randomly included and compared with socio-demographic and clinical data of the patients, using Chi-square and Fisher’s exact tests as the statistical tool. Analysis found no significant association between MDRPA with ages, gender and ethnicity of patients (p>0.050). Other risk factors being investigated were invasive procedure, immunosuppression, bedridden and clinical diagnosis such as central nervous- and respiratory-system disorder, as well as antibiotic exposure during hospitalization and duration of hospital stay with only the last two were found to have significant association (p=0.035 and 0.019, respectively). Some other studies also reported a similar association indicating that the two factors could serve as an important predictive tool for isolation of MDRPA. More studies involving a larger sampling size are warranted to establish the association. |
| first_indexed | 2024-03-06T08:31:51Z |
| format | Article |
| id | upm.eprints-35281 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:31:51Z |
| publishDate | 2015 |
| publisher | Universiti Kebangsaan Malaysia Press |
| record_format | dspace |
| spelling | upm.eprints-352812015-12-31T04:52:33Z http://psasir.upm.edu.my/id/eprint/35281/ Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital Mohd Desa, Mohd Nasir M. H. , Nurnajwa Lay, J. Teoh, J. C. Amin Nordin, Syafinaz Mohd Taib, Niazlin A case-control study was conducted based on medical cases of 100 hospitalized patients with Pseudomonas aeruginosa-isolation at a Malaysian hospital. Cases with 50 multidrug-resistant P. aeruginosa MDRPA and 50 non-multidrug-resistant P. aeruginosa (NMDRPA) were randomly included and compared with socio-demographic and clinical data of the patients, using Chi-square and Fisher’s exact tests as the statistical tool. Analysis found no significant association between MDRPA with ages, gender and ethnicity of patients (p>0.050). Other risk factors being investigated were invasive procedure, immunosuppression, bedridden and clinical diagnosis such as central nervous- and respiratory-system disorder, as well as antibiotic exposure during hospitalization and duration of hospital stay with only the last two were found to have significant association (p=0.035 and 0.019, respectively). Some other studies also reported a similar association indicating that the two factors could serve as an important predictive tool for isolation of MDRPA. More studies involving a larger sampling size are warranted to establish the association. Universiti Kebangsaan Malaysia Press 2015-02 Article NonPeerReviewed Mohd Desa, Mohd Nasir and M. H. , Nurnajwa and Lay, J. and Teoh, J. C. and Amin Nordin, Syafinaz and Mohd Taib, Niazlin (2015) Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital. Sains Malaysiana, 44 (2). pp. 257-260. ISSN 0026-6039 http://www.ukm.my/jsm/malay_journals/jilid44bil2_2015/Jilid44Bil2_2015ms257-260.html |
| spellingShingle | Mohd Desa, Mohd Nasir M. H. , Nurnajwa Lay, J. Teoh, J. C. Amin Nordin, Syafinaz Mohd Taib, Niazlin Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title | Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title_full | Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title_fullStr | Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title_full_unstemmed | Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title_short | Risk factors for multidrug-resistant Pseudomonas aeruginosa among hospitalized patients at a Malaysian hospital |
| title_sort | risk factors for multidrug resistant pseudomonas aeruginosa among hospitalized patients at a malaysian hospital |
| work_keys_str_mv | AT mohddesamohdnasir riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital AT mhnurnajwa riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital AT layj riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital AT teohjc riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital AT aminnordinsyafinaz riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital AT mohdtaibniazlin riskfactorsformultidrugresistantpseudomonasaeruginosaamonghospitalizedpatientsatamalaysianhospital |