Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode
The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe3O4/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. The Fe3O4/rGO nanocomposite was synthesized via a simple, one step in-situ wet chemi...
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| Format: | Article |
| Language: | English |
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MDPI
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/35381/1/Simultaneous%20Electrochemical%20Detection%20of%20Dopamine%20and.pdf |
| _version_ | 1825948635519516672 |
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| author | Teo, Peik See Pandikumar, Alagarsamy Huang, Nay Ming Lim, Hong Ngee Sulaiman, Yusran |
| author_facet | Teo, Peik See Pandikumar, Alagarsamy Huang, Nay Ming Lim, Hong Ngee Sulaiman, Yusran |
| author_sort | Teo, Peik See |
| collection | UPM |
| description | The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe3O4/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. The Fe3O4/rGO nanocomposite was synthesized via a simple, one step in-situ wet chemical method and characterized by different techniques. The presence of Fe3O4 nanoparticles on the surface of rGO sheets was confirmed by FESEM and TEM images. The electrochemical behavior of Fe3O4/rGO/GCE towards electrocatalytic oxidation of DA was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) analysis. The electrochemical studies revealed that the Fe3O4/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe3O4 and rGO. This implies that Fe3O4/rGO/GCE could exhibit excellent electrocatalytic activity and remarkable electron transfer kinetics towards the oxidation of DA. Moreover, the modified sensor electrode portrayed sensitivity and selectivity for simultaneous determination of AA and DA. The observed DPVs response linearly depends on AA and DA concentration in the range of 1–9 mM and 0.5–100 µM, with correlation coefficients of 0.995 and 0.996, respectively. The detection limit of (S/N = 3) was found to be 0.42 and 0.12 µM for AA and DA, respectively. |
| first_indexed | 2024-03-06T08:32:09Z |
| format | Article |
| id | upm.eprints-35381 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:32:09Z |
| publishDate | 2014 |
| publisher | MDPI |
| record_format | dspace |
| spelling | upm.eprints-353812016-03-03T13:54:48Z http://psasir.upm.edu.my/id/eprint/35381/ Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode Teo, Peik See Pandikumar, Alagarsamy Huang, Nay Ming Lim, Hong Ngee Sulaiman, Yusran The fabrication of an electrochemical sensor based on an iron oxide/graphene modified glassy carbon electrode (Fe3O4/rGO/GCE) and its simultaneous detection of dopamine (DA) and ascorbic acid (AA) is described here. The Fe3O4/rGO nanocomposite was synthesized via a simple, one step in-situ wet chemical method and characterized by different techniques. The presence of Fe3O4 nanoparticles on the surface of rGO sheets was confirmed by FESEM and TEM images. The electrochemical behavior of Fe3O4/rGO/GCE towards electrocatalytic oxidation of DA was investigated by cyclic voltammetry (CV) and differential pulse voltammetry (DPV) analysis. The electrochemical studies revealed that the Fe3O4/rGO/GCE dramatically increased the current response against the DA, due to the synergistic effect emerged between Fe3O4 and rGO. This implies that Fe3O4/rGO/GCE could exhibit excellent electrocatalytic activity and remarkable electron transfer kinetics towards the oxidation of DA. Moreover, the modified sensor electrode portrayed sensitivity and selectivity for simultaneous determination of AA and DA. The observed DPVs response linearly depends on AA and DA concentration in the range of 1–9 mM and 0.5–100 µM, with correlation coefficients of 0.995 and 0.996, respectively. The detection limit of (S/N = 3) was found to be 0.42 and 0.12 µM for AA and DA, respectively. MDPI 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/35381/1/Simultaneous%20Electrochemical%20Detection%20of%20Dopamine%20and.pdf Teo, Peik See and Pandikumar, Alagarsamy and Huang, Nay Ming and Lim, Hong Ngee and Sulaiman, Yusran (2014) Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode. Sensors, 14 (8). pp. 15227-15243. ISSN 1424-8220; ESSN:1424-8220 http://www.mdpi.com/1424-8220/14/8/15227 10.3390/s140815227 |
| spellingShingle | Teo, Peik See Pandikumar, Alagarsamy Huang, Nay Ming Lim, Hong Ngee Sulaiman, Yusran Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title | Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title_full | Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title_fullStr | Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title_full_unstemmed | Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title_short | Simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide/reduced graphene oxide modified glassy carbon electrode |
| title_sort | simultaneous electrochemical detection of dopamine and ascorbic acid using iron oxide reduced graphene oxide modified glassy carbon electrode |
| url | http://psasir.upm.edu.my/id/eprint/35381/1/Simultaneous%20Electrochemical%20Detection%20of%20Dopamine%20and.pdf |
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