The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus
INTRODUCTION The aim of this study was to evaluate the health-related quality of life (HRQoL) of Malaysian patients with type 2 diabetes mellitus (T2DM) who have cardiovascular disease (CVD), as well as identify the determinants of HRQoL among this cohort of patients. METHODS This study was an an...
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| Format: | Article |
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Singapore Medical Association
2014
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| author | Tan, Mun Chieng Ng, Ooi Chuan Wong, Teck Wee Abdul Rahman, Hejar Anthony, Joseph Sintonen, Harri |
| author_facet | Tan, Mun Chieng Ng, Ooi Chuan Wong, Teck Wee Abdul Rahman, Hejar Anthony, Joseph Sintonen, Harri |
| author_sort | Tan, Mun Chieng |
| collection | UPM |
| description | INTRODUCTION
The aim of this study was to evaluate the health-related quality of life (HRQoL) of Malaysian patients with type 2 diabetes mellitus (T2DM) who have cardiovascular disease (CVD), as well as identify the determinants of HRQoL among this cohort of patients.
METHODS
This study was an analytical cross-sectional study involving 313 patients aged 30–78 years (150 men, 163 women; mean age 55.7 ± 9.2 years) who were diagnosed with T2DM (mean duration of T2DM 10.1 ± 8.1 years) at two tertiary Malaysian government hospitals. The patients’ sociodemographic, lifestyle, clinical and laboratory data were collected prospectively from medical records and via face-to-face interviews. HRQoL was assessed using the 15D instrument – a generic, 15-dimensional and standardised measure of HRQoL that can be used as both a profile and a single index score measure.
RESULTS
T2DM patients with CVD were found to have significantly lower 15D HRQoL scores than their non-CVD counterparts (p < 0.001). The HRQoL of T2DM patients with CVD was significantly lower than those without CVD (p < 0.05) in all of the 15 dimensions of the 15D instrument. Multinomial logistic regression analysis using backward stepwise method revealed a significant association between CVD and impaired HRQoL (odds ratio [OR] 11.746, 95% confidence interval [CI] 4.898–28.167). Age (OR 1.095, 95% CI 1.054–1.137), duration of T2DM (OR 1.085, 95% CI 1.032–1.140), ethnicity (OR 0.411, 95% CI 0.187–0.903), body mass index (OR 1.074, 95% CI 1.006–1.148), and physical activity level (OR 3.506, 95% CI 1.415–8.689) were also significant predictors of HRQoL.
CONCLUSION
In T2DM patients, the presence of CVD was significantly associated with a lower HRQoL. Therefore, the importance of tertiary prevention to minimise the potential deterioration of the HRQoL of T2DM patients with CVD should be highly emphasised. |
| first_indexed | 2024-03-06T08:32:55Z |
| format | Article |
| id | upm.eprints-35632 |
| institution | Universiti Putra Malaysia |
| last_indexed | 2024-03-06T08:32:55Z |
| publishDate | 2014 |
| publisher | Singapore Medical Association |
| record_format | dspace |
| spelling | upm.eprints-356322016-01-18T03:44:05Z http://psasir.upm.edu.my/id/eprint/35632/ The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus Tan, Mun Chieng Ng, Ooi Chuan Wong, Teck Wee Abdul Rahman, Hejar Anthony, Joseph Sintonen, Harri INTRODUCTION The aim of this study was to evaluate the health-related quality of life (HRQoL) of Malaysian patients with type 2 diabetes mellitus (T2DM) who have cardiovascular disease (CVD), as well as identify the determinants of HRQoL among this cohort of patients. METHODS This study was an analytical cross-sectional study involving 313 patients aged 30–78 years (150 men, 163 women; mean age 55.7 ± 9.2 years) who were diagnosed with T2DM (mean duration of T2DM 10.1 ± 8.1 years) at two tertiary Malaysian government hospitals. The patients’ sociodemographic, lifestyle, clinical and laboratory data were collected prospectively from medical records and via face-to-face interviews. HRQoL was assessed using the 15D instrument – a generic, 15-dimensional and standardised measure of HRQoL that can be used as both a profile and a single index score measure. RESULTS T2DM patients with CVD were found to have significantly lower 15D HRQoL scores than their non-CVD counterparts (p < 0.001). The HRQoL of T2DM patients with CVD was significantly lower than those without CVD (p < 0.05) in all of the 15 dimensions of the 15D instrument. Multinomial logistic regression analysis using backward stepwise method revealed a significant association between CVD and impaired HRQoL (odds ratio [OR] 11.746, 95% confidence interval [CI] 4.898–28.167). Age (OR 1.095, 95% CI 1.054–1.137), duration of T2DM (OR 1.085, 95% CI 1.032–1.140), ethnicity (OR 0.411, 95% CI 0.187–0.903), body mass index (OR 1.074, 95% CI 1.006–1.148), and physical activity level (OR 3.506, 95% CI 1.415–8.689) were also significant predictors of HRQoL. CONCLUSION In T2DM patients, the presence of CVD was significantly associated with a lower HRQoL. Therefore, the importance of tertiary prevention to minimise the potential deterioration of the HRQoL of T2DM patients with CVD should be highly emphasised. Singapore Medical Association 2014-04 Article PeerReviewed Tan, Mun Chieng and Ng, Ooi Chuan and Wong, Teck Wee and Abdul Rahman, Hejar and Anthony, Joseph and Sintonen, Harri (2014) The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus. Singapore Medical Journal, 55 (4). pp. 209-216. ISSN 0037-5675 |
| spellingShingle | Tan, Mun Chieng Ng, Ooi Chuan Wong, Teck Wee Abdul Rahman, Hejar Anthony, Joseph Sintonen, Harri The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title | The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title_full | The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title_fullStr | The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title_full_unstemmed | The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title_short | The association of cardiovascular disease with impaired health-related quality of life among patients with type 2 diabetes mellitus |
| title_sort | association of cardiovascular disease with impaired health related quality of life among patients with type 2 diabetes mellitus |
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