An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination

An amperometric biosensor for the quantitative measurement of glucose is reported. The biosensor is based on a biocomposite that is homogeneous and easily prepared. This biocomposite is made of polyethylene glycol (PEG), Cetyl trimethylammonium bromide (CTAB), glucose oxidase (GOx), and zirconium ox...

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Hoofdauteurs: Ahmad, Nor Monica, Abdullah, Jaafar, Ramli, Noor Izaanin, Abd Rahman, Samsulida, Azmi, Nur Ellina, Ariffin, Nurhayati
Formaat: Artikel
Taal:English
Gepubliceerd in: American Scientific Publishers 2014
Online toegang:http://psasir.upm.edu.my/id/eprint/36391/1/An%20approach%20of%20zirconium%20oxide.pdf
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author Ahmad, Nor Monica
Abdullah, Jaafar
Ramli, Noor Izaanin
Abd Rahman, Samsulida
Azmi, Nur Ellina
Ariffin, Nurhayati
author_facet Ahmad, Nor Monica
Abdullah, Jaafar
Ramli, Noor Izaanin
Abd Rahman, Samsulida
Azmi, Nur Ellina
Ariffin, Nurhayati
author_sort Ahmad, Nor Monica
collection UPM
description An amperometric biosensor for the quantitative measurement of glucose is reported. The biosensor is based on a biocomposite that is homogeneous and easily prepared. This biocomposite is made of polyethylene glycol (PEG), Cetyl trimethylammonium bromide (CTAB), glucose oxidase (GOx), and zirconium oxide (ZrO2) nanoparticles. Effect of applied potential, pH, nanocomposite layer, ratio of zirconium oxide nanoparticles (ZrO2) to polyethylene glycol (PEG), concentration of ferrocenecarboxaldehyde (Fc) and concentration of enzyme that governed the analytical performance of the biosensor have been studied. The biosensor was applied to detect glucose with a linear calibration range from 0.1 mM to 12 mM and limit of detection 0.04 mM. The variation coefficient (RSD) for repeatability was 7.5% for ten successive assays while 6.01% (n = 5) for reproducibility test demonstrating that the biosensor fabrication process is reproducible. Common interfering compounds on the amperometric response of the sensor were investigated and discussed herein.
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spelling upm.eprints-363912015-08-21T03:17:09Z http://psasir.upm.edu.my/id/eprint/36391/ An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination Ahmad, Nor Monica Abdullah, Jaafar Ramli, Noor Izaanin Abd Rahman, Samsulida Azmi, Nur Ellina Ariffin, Nurhayati An amperometric biosensor for the quantitative measurement of glucose is reported. The biosensor is based on a biocomposite that is homogeneous and easily prepared. This biocomposite is made of polyethylene glycol (PEG), Cetyl trimethylammonium bromide (CTAB), glucose oxidase (GOx), and zirconium oxide (ZrO2) nanoparticles. Effect of applied potential, pH, nanocomposite layer, ratio of zirconium oxide nanoparticles (ZrO2) to polyethylene glycol (PEG), concentration of ferrocenecarboxaldehyde (Fc) and concentration of enzyme that governed the analytical performance of the biosensor have been studied. The biosensor was applied to detect glucose with a linear calibration range from 0.1 mM to 12 mM and limit of detection 0.04 mM. The variation coefficient (RSD) for repeatability was 7.5% for ten successive assays while 6.01% (n = 5) for reproducibility test demonstrating that the biosensor fabrication process is reproducible. Common interfering compounds on the amperometric response of the sensor were investigated and discussed herein. American Scientific Publishers 2014-11 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36391/1/An%20approach%20of%20zirconium%20oxide.pdf Ahmad, Nor Monica and Abdullah, Jaafar and Ramli, Noor Izaanin and Abd Rahman, Samsulida and Azmi, Nur Ellina and Ariffin, Nurhayati (2014) An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination. Sensor Letters, 12 (11). pp. 1590-1596. ISSN 1546-198X; ESSN:1546-1971 10.1166/sl.2014.3381
spellingShingle Ahmad, Nor Monica
Abdullah, Jaafar
Ramli, Noor Izaanin
Abd Rahman, Samsulida
Azmi, Nur Ellina
Ariffin, Nurhayati
An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title_full An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title_fullStr An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title_full_unstemmed An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title_short An approach of zirconium oxide/polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
title_sort approach of zirconium oxide polyethylene glycol nanocomposite film on screen printed carbon electrode and its application in glucose determination
url http://psasir.upm.edu.my/id/eprint/36391/1/An%20approach%20of%20zirconium%20oxide.pdf
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