Chemical characterization and antioxidant activity of three medicinal Apiaceae species
Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three differe...
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| Format: | Article |
| Language: | English |
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Elsevier
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf |
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| author | Maulidiani, Abas, Faridah Khatib, Alfi Shaari, Khozirah Lajis, Md Nordin |
| author_facet | Maulidiani, Abas, Faridah Khatib, Alfi Shaari, Khozirah Lajis, Md Nordin |
| author_sort | Maulidiani, |
| collection | UPM |
| description | Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three different Pegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabolite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-type triterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotyle species consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due to the difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evaluated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, and xanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potent antioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 μg/ml; XOI = 87.68 μg/ml) as compared to H. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 μg/ml; XOI = 32.23 μg/ml) and H. sibthorpioides (TPC = 56.23 mg/100 g DW; DPPH = 37.86 μg/ml; XOI = 14.73. μg/ml). |
| first_indexed | 2024-03-06T08:36:19Z |
| format | Article |
| id | upm.eprints-36771 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:36:19Z |
| publishDate | 2014 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | upm.eprints-367712015-10-06T03:46:28Z http://psasir.upm.edu.my/id/eprint/36771/ Chemical characterization and antioxidant activity of three medicinal Apiaceae species Maulidiani, Abas, Faridah Khatib, Alfi Shaari, Khozirah Lajis, Md Nordin Centella asiatica (‘Pegaga’ = Malaysia) is well known plant that has been used as one of the ingredients in pharmaceutical and cosmetic industries. Using liquid chromatography with diode array and electrospray ionization/mass spectrometry (LC–DAD–ESI/MS) analysis, chemical profiling of three different Pegaga extracts (C. asiatica, H. bonariensis and H. sibthorpioides) revealed variations in their metabolite profile. Our findings showed that triterpenes of C. asiatica were characterized by the ursane-type triterpenes (madecassoside, asiaticoside, madecassic acid, and asiatic acid), while the two Hydrocotyle species consisted of oleanane-type triterpenes (barrigenol derivatives). Other variations are due to the difference in phenolic and flavonoid constituents. The three Pegaga extracts were also evaluated for their total phenolic content (TPC), 1,1-diphenyl-2-picrylhydrazyl (DPPH) free radicals, and xanthine oxidase inhibition (XOI) activities. The results showed that C. asiatica has the most potent antioxidant activity (TPC = 72.09 mg/100 g DW; DPPH = 72.99 μg/ml; XOI = 87.68 μg/ml) as compared to H. bonariensis (TPC = 28.55 mg/100 g DW; DPPH = 22.43 μg/ml; XOI = 32.23 μg/ml) and H. sibthorpioides (TPC = 56.23 mg/100 g DW; DPPH = 37.86 μg/ml; XOI = 14.73. μg/ml). Elsevier 2014-04 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf Maulidiani, and Abas, Faridah and Khatib, Alfi and Shaari, Khozirah and Lajis, Md Nordin (2014) Chemical characterization and antioxidant activity of three medicinal Apiaceae species. Industrial Crops and Products, 55. pp. 238-247. ISSN 0926-6690; ESSN: 1872-633X 10.1016/j.indcrop.2014.02.013 |
| spellingShingle | Maulidiani, Abas, Faridah Khatib, Alfi Shaari, Khozirah Lajis, Md Nordin Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_full | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_fullStr | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_full_unstemmed | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_short | Chemical characterization and antioxidant activity of three medicinal Apiaceae species |
| title_sort | chemical characterization and antioxidant activity of three medicinal apiaceae species |
| url | http://psasir.upm.edu.my/id/eprint/36771/1/Chemical%20characterization%20and%20antioxidant%20activity%20of%20three%20medicinal%20Apiaceae%20species.pdf |
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