Contrast enhancement of magnetic resonance imaging (MRI) of polymer gel dosimeter by adding Platinum nano- particles

In this research different concentrations of Platinum nanoparticles (Pt-NPs) embedded in PAGAT polymer gel and irradiated with Cobalt -60 (60Co). The OD of samples indicate significant dose enhancement caused by Pt-NPs. Different concentrations of Pt-NPs were investigated: 0.5×10−2,1×10−2 2×10−2 and...

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Bibliographic Details
Main Authors: Deyhimihaghighi, N., Mohd Noor, Noramaliza, Soltani, Nader, Jorfi, Rahele, Haghiri, Maryam Erfani, Adenan, Mohd Zulfadli, Saion, Elias, Khandaker, Mayeen Uddin
Format: Article
Language:English
Published: Institute of Physics Publishing 2014
Online Access:http://psasir.upm.edu.my/id/eprint/36902/1/Contrast%20enhancement%20of%20magnetic%20resonance%20imaging%20%28MRI%29.pdf
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Summary:In this research different concentrations of Platinum nanoparticles (Pt-NPs) embedded in PAGAT polymer gel and irradiated with Cobalt -60 (60Co). The OD of samples indicate significant dose enhancement caused by Pt-NPs. Different concentrations of Pt-NPs were investigated: 0.5×10−2,1×10−2 2×10−2 and 3×10−2 mg/l and these were presented the enhancement in OD by the factor of 11.56, 27.10, 15.84 and 10.07 respectively. As the mean energy of 60Co is 1.25 MeV and atomic number (Z) of Pt is 78, the predominant effect will be Compton effect and Photoelectric cannot occurred. This work studied the feasibility of using PAGAT polymer gel combined with Pt-NPs as a suitable tool to perform dosimetric investigation of nanoparticles application in radiotherapy as dosimeter and dose enhancer.