Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study
This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography (18F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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IOP Publishing
2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/37499/1/37499.pdf |
| _version_ | 1825949046190112768 |
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| author | Mahmud, Mohd Hafizi Nordin, Abdul Jalil Ahmad Saad, Fathinul Fikri Azman, Ahmad Zaid Fattah |
| author_facet | Mahmud, Mohd Hafizi Nordin, Abdul Jalil Ahmad Saad, Fathinul Fikri Azman, Ahmad Zaid Fattah |
| author_sort | Mahmud, Mohd Hafizi |
| collection | UPM |
| description | This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography (18F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent 18F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDIvol), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body 18F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques. |
| first_indexed | 2024-03-06T08:38:32Z |
| format | Article |
| id | upm.eprints-37499 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:38:32Z |
| publishDate | 2014 |
| publisher | IOP Publishing |
| record_format | dspace |
| spelling | upm.eprints-374992015-12-16T08:39:06Z http://psasir.upm.edu.my/id/eprint/37499/ Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study Mahmud, Mohd Hafizi Nordin, Abdul Jalil Ahmad Saad, Fathinul Fikri Azman, Ahmad Zaid Fattah This study aims to estimate the radiation effective dose resulting from whole body fluorine-18 flourodeoxyglucose Positron Emission Tomography (18F-FDG PET) scanning as compared to conservative Computed Tomography (CT) techniques in evaluating oncology patients. We reviewed 19 oncology patients who underwent 18F-FDG PET/CT at our centre for cancer staging. Internal and external doses were estimated using radioactivity of injected FDG and volume CT Dose Index (CTDIvol), respectively with employment of the published and modified dose coefficients. The median differences of dose among the conservative CT and PET protocols were determined using Kruskal Wallis test with p < 0.05 considered as significant. The median (interquartile range, IQR) effective doses of non-contrasted CT, contrasted CT and PET scanning protocols were 7.50 (9.35) mSv, 9.76 (3.67) mSv and 6.30 (1.20) mSv, respectively, resulting in the total dose of 21.46 (8.58) mSv. Statistically significant difference was observed in the median effective dose between the three protocols (p < 0.01). The effective doses of whole body 18F-FDG PET technique may be effective the lowest amongst the conventional CT imaging techniques. IOP Publishing 2014 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/37499/1/37499.pdf Mahmud, Mohd Hafizi and Nordin, Abdul Jalil and Ahmad Saad, Fathinul Fikri and Azman, Ahmad Zaid Fattah (2014) Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study. Journal of Physics: Conference Series, 546. art. no. 012008. pp. 1-6. ISSN 1742-6588; ESSN: 1742-6596 http://iopscience.iop.org/article/10.1088/1742-6596/546/1/012008/meta 10.1088/1742-6596/546/1/012008 |
| spellingShingle | Mahmud, Mohd Hafizi Nordin, Abdul Jalil Ahmad Saad, Fathinul Fikri Azman, Ahmad Zaid Fattah Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title | Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title_full | Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title_fullStr | Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title_full_unstemmed | Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title_short | Estimation of patient radiation dose from whole body 18F-FDG PET/CT examination in cancer imaging: a preliminary study |
| title_sort | estimation of patient radiation dose from whole body 18f fdg pet ct examination in cancer imaging a preliminary study |
| url | http://psasir.upm.edu.my/id/eprint/37499/1/37499.pdf |
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