Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks

Background: The Ts1Cje mouse model of Down syndrome (DS) has partial triplication of mouse chromosome 16 (MMU16), which is partially homologous to human chromosome 21. These mice develop various neuropathological features identified in DS individuals. We analysed the effect of partial triplication o...

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Main Authors: Ling, King Hwa, Hewitt, Chelsee Ann, Tan, Kai Leng, Cheah, Pike See, Vidyadaran, Sharmili, Lai, Mei I., Lee, Han Chung, Simpson, Ken, Hyde, Lavinia, Pritchard, Melanie A., Smyth, Gordon K., Thomas, Tim, Scott, Hamish S.
Format: Article
Language:English
Published: BioMed Central 2014
Online Access:http://psasir.upm.edu.my/id/eprint/37726/1/Functional%20transcriptome%20analysis%20of%20the%20postnatal%20brain%20of%20the%20Ts1Cje%20mouse%20model%20for%20Down%20syndrome%20reveals%20global%20disruption%20of%20interferon.pdf

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