Adverse effects of imidocarb dipropionate (Imizol®) in a dog

One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemo...

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Main Authors: Abdullah, Abdul Salam, Abdul Rahman, Sheikh Omar, Baggot, J. Desmond, Zamri, M.
Format: Article
Language:English
English
Published: Springer 1984
Online Access:http://psasir.upm.edu.my/id/eprint/39503/1/10.%20Adverse%20effects%20of%20imidocarb%20dipropionate%20%28Imizol%C2%AE%29%20in%20a%20dog.pdf
http://psasir.upm.edu.my/id/eprint/39503/7/BF02214695.pdf
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author Abdullah, Abdul Salam
Abdul Rahman, Sheikh Omar
Baggot, J. Desmond
Zamri, M.
author_facet Abdullah, Abdul Salam
Abdul Rahman, Sheikh Omar
Baggot, J. Desmond
Zamri, M.
author_sort Abdullah, Abdul Salam
collection UPM
description One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action.
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spelling upm.eprints-395032024-08-05T08:08:10Z http://psasir.upm.edu.my/id/eprint/39503/ Adverse effects of imidocarb dipropionate (Imizol®) in a dog Abdullah, Abdul Salam Abdul Rahman, Sheikh Omar Baggot, J. Desmond Zamri, M. One of 13 healthy dogs used in a pharmacokinetic study of imidocarb dipropionate died due to difficulty in breathing, tachycardia, weakness and profuse diarrhoea. Autopsy findings showed marked pulmonary congestion and oedema. Kidneys were grossly enlarged and markedly congested with extensive haemorrhage in the cortex and medulla. Marked tubulonephrosis was also exhibited microscopically. Liver and spleen were moderately enlarged and congested. The adverse effects of imidocarb may be due to excessive acetylcholine action. Springer 1984 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/39503/1/10.%20Adverse%20effects%20of%20imidocarb%20dipropionate%20%28Imizol%C2%AE%29%20in%20a%20dog.pdf text en http://psasir.upm.edu.my/id/eprint/39503/7/BF02214695.pdf Abdullah, Abdul Salam and Abdul Rahman, Sheikh Omar and Baggot, J. Desmond and Zamri, M. (1984) Adverse effects of imidocarb dipropionate (Imizol®) in a dog. Veterinary Research Communications, 8 (1). pp. 55-59. ISSN 0165-7380; ESSN: 1573-7446 10.1007/BF02214695
spellingShingle Abdullah, Abdul Salam
Abdul Rahman, Sheikh Omar
Baggot, J. Desmond
Zamri, M.
Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title_full Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title_fullStr Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title_full_unstemmed Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title_short Adverse effects of imidocarb dipropionate (Imizol®) in a dog
title_sort adverse effects of imidocarb dipropionate imizol r in a dog
url http://psasir.upm.edu.my/id/eprint/39503/1/10.%20Adverse%20effects%20of%20imidocarb%20dipropionate%20%28Imizol%C2%AE%29%20in%20a%20dog.pdf
http://psasir.upm.edu.my/id/eprint/39503/7/BF02214695.pdf
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