Antioxidative activity of carbazoles from Murraya koenigii leaves
The antioxidative properties of the leaves extracts of Murraya koenigii using different solvents were evaluated based on the oil stability index (OSI) together with their radical scavenging ability against 1-1-diphenyl-2-picrylhydrazyl (DPPH). The methylene chloride (CH2Cl2) extract and the ethyl ac...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2001
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| Online Access: | http://psasir.upm.edu.my/id/eprint/39980/1/Antioxidative%20activity%20of%20carbazoles%20from%20Murraya%20koenigii%20leaves.pdf |
| _version_ | 1825949513188114432 |
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| author | Tachibana, Yukari Kikuzaki, Hiroe Lajis, Nordin Nakatani, Nobuji |
| author_facet | Tachibana, Yukari Kikuzaki, Hiroe Lajis, Nordin Nakatani, Nobuji |
| author_sort | Tachibana, Yukari |
| collection | UPM |
| description | The antioxidative properties of the leaves extracts of Murraya koenigii using different solvents were evaluated based on the oil stability index (OSI) together with their radical scavenging ability against 1-1-diphenyl-2-picrylhydrazyl (DPPH). The methylene chloride (CH2Cl2) extract and the ethyl acetate (EtOAc) soluble fraction of the 70% acetone extract significantly prolonged the OSI values comparable to those of α-tocopherol and BHT. Five carbazole alkaloids were isolated from the CH2Cl2 extract and their structures were identified to be euchrestine B (1), bismurrayafoline E (2), mahanine (3), mahanimbicine (4), and mahanimbine (5) based on 1H and 13C NMR and mass (MS) spectral data. The OSI value of carbazoles at 110 °C decreased in the order 1 and 3 > α-tocopherol > BHT > 2 > 4, 5 and control. It is assumed that compounds 1 and 3 contributed to the high OSI value of the CH2Cl2 extract of M. koenigii. The DPPH radical scavenging activity for these carbazoles was in the order ascorbic acid > 2 > 1, 3 and α-tocopherol > BHT > 4 and 5. |
| first_indexed | 2024-03-06T08:45:43Z |
| format | Article |
| id | upm.eprints-39980 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:45:43Z |
| publishDate | 2001 |
| publisher | American Chemical Society |
| record_format | dspace |
| spelling | upm.eprints-399802015-08-26T02:57:37Z http://psasir.upm.edu.my/id/eprint/39980/ Antioxidative activity of carbazoles from Murraya koenigii leaves Tachibana, Yukari Kikuzaki, Hiroe Lajis, Nordin Nakatani, Nobuji The antioxidative properties of the leaves extracts of Murraya koenigii using different solvents were evaluated based on the oil stability index (OSI) together with their radical scavenging ability against 1-1-diphenyl-2-picrylhydrazyl (DPPH). The methylene chloride (CH2Cl2) extract and the ethyl acetate (EtOAc) soluble fraction of the 70% acetone extract significantly prolonged the OSI values comparable to those of α-tocopherol and BHT. Five carbazole alkaloids were isolated from the CH2Cl2 extract and their structures were identified to be euchrestine B (1), bismurrayafoline E (2), mahanine (3), mahanimbicine (4), and mahanimbine (5) based on 1H and 13C NMR and mass (MS) spectral data. The OSI value of carbazoles at 110 °C decreased in the order 1 and 3 > α-tocopherol > BHT > 2 > 4, 5 and control. It is assumed that compounds 1 and 3 contributed to the high OSI value of the CH2Cl2 extract of M. koenigii. The DPPH radical scavenging activity for these carbazoles was in the order ascorbic acid > 2 > 1, 3 and α-tocopherol > BHT > 4 and 5. American Chemical Society 2001 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/39980/1/Antioxidative%20activity%20of%20carbazoles%20from%20Murraya%20koenigii%20leaves.pdf Tachibana, Yukari and Kikuzaki, Hiroe and Lajis, Nordin and Nakatani, Nobuji (2001) Antioxidative activity of carbazoles from Murraya koenigii leaves. Journal of Agricultural and Food Chemistry, 49 (11). pp. 5589-5594. ISSN 0021-8561; ESSN: 1520-5118 http://pubs.acs.org/doi/abs/10.1021/jf010621r 10.1021/jf010621r |
| spellingShingle | Tachibana, Yukari Kikuzaki, Hiroe Lajis, Nordin Nakatani, Nobuji Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title | Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title_full | Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title_fullStr | Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title_full_unstemmed | Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title_short | Antioxidative activity of carbazoles from Murraya koenigii leaves |
| title_sort | antioxidative activity of carbazoles from murraya koenigii leaves |
| url | http://psasir.upm.edu.my/id/eprint/39980/1/Antioxidative%20activity%20of%20carbazoles%20from%20Murraya%20koenigii%20leaves.pdf |
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