18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess

Chronic osteomyelitis (Brodie's abscess) is essentially a problem of diagnosis, and there may be considerable difficulty in distinguishing it from other benign and malignant bone lesions. Early diagnosis of Brodie's abscess is deemed important as the disease has a good curative potential f...

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Main Authors: Ahmad Saad, Fathinul Fikri, Nordin, Abdul Jalil
Format: Article
Language:English
Published: Department of Biomedical Imaging (Radiology), Faculty of Medicine, University of Malaya 2010
Online Access:http://psasir.upm.edu.my/id/eprint/40447/1/18F-FDG%20PETCT%20as%20a%20potential%20valuable%20adjunct%20to%20MRI%20in%20characterising%20the%20Brodie%27s%20abscess.pdf
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author Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
author_facet Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
author_sort Ahmad Saad, Fathinul Fikri
collection UPM
description Chronic osteomyelitis (Brodie's abscess) is essentially a problem of diagnosis, and there may be considerable difficulty in distinguishing it from other benign and malignant bone lesions. Early diagnosis of Brodie's abscess is deemed important as the disease has a good curative potential following an appropriate antibiotic treatment. Of late, PET/CT using 18F-FDG is taking a centre stage in the imaging of bone infection though documentation on its role in characterising the feature of Brodie's abscess is exceedingly scarce. On the other hand, it is well known that MRI imaging plays a very important role in distinguishing abscess loculation from malignancy. The authors present the case of a 13-year-old boy with pain in the right heel for few months. Radiograph of the right foot revealed a lucent focus with sclerotic margin in the right calcaneum. MRI T1-weighted images were inconclusive of penumbra sign to characterise abscess cavity due to the small volume lesion. Whole-body 18F-FDG PET/CT scan showed multiple small avid lesions at the margin of the sclerotic rim in the right calcaneum. Final diagnosis of Brodie's abscess with Klebsiella culture was confirmed via bone debridement.
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spelling upm.eprints-404472015-09-18T04:02:06Z http://psasir.upm.edu.my/id/eprint/40447/ 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess Ahmad Saad, Fathinul Fikri Nordin, Abdul Jalil Chronic osteomyelitis (Brodie's abscess) is essentially a problem of diagnosis, and there may be considerable difficulty in distinguishing it from other benign and malignant bone lesions. Early diagnosis of Brodie's abscess is deemed important as the disease has a good curative potential following an appropriate antibiotic treatment. Of late, PET/CT using 18F-FDG is taking a centre stage in the imaging of bone infection though documentation on its role in characterising the feature of Brodie's abscess is exceedingly scarce. On the other hand, it is well known that MRI imaging plays a very important role in distinguishing abscess loculation from malignancy. The authors present the case of a 13-year-old boy with pain in the right heel for few months. Radiograph of the right foot revealed a lucent focus with sclerotic margin in the right calcaneum. MRI T1-weighted images were inconclusive of penumbra sign to characterise abscess cavity due to the small volume lesion. Whole-body 18F-FDG PET/CT scan showed multiple small avid lesions at the margin of the sclerotic rim in the right calcaneum. Final diagnosis of Brodie's abscess with Klebsiella culture was confirmed via bone debridement. Department of Biomedical Imaging (Radiology), Faculty of Medicine, University of Malaya 2010-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40447/1/18F-FDG%20PETCT%20as%20a%20potential%20valuable%20adjunct%20to%20MRI%20in%20characterising%20the%20Brodie%27s%20abscess.pdf Ahmad Saad, Fathinul Fikri and Nordin, Abdul Jalil (2010) 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess. Biomedical Imaging and Intervention Journal, 6 (3). ISSN 1823-5530
spellingShingle Ahmad Saad, Fathinul Fikri
Nordin, Abdul Jalil
18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title_full 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title_fullStr 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title_full_unstemmed 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title_short 18F-FDG PET/CT as a potential valuable adjunct to MRI in characterising the Brodie's abscess
title_sort 18f fdg pet ct as a potential valuable adjunct to mri in characterising the brodie s abscess
url http://psasir.upm.edu.my/id/eprint/40447/1/18F-FDG%20PETCT%20as%20a%20potential%20valuable%20adjunct%20to%20MRI%20in%20characterising%20the%20Brodie%27s%20abscess.pdf
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