Alkaloids from Piper nigrum and Piper betle
An investigation, on the roots of Piper nigrum and the aerial parts of Piper betle, has yielded several alkaloids. The dried root sample of Piper nigrum was extracted using various solvents in increasing polarity. The dried aerial part of Piper betle was extracted using the Soxhlet extraction method...
| Main Authors: | , , , |
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| Format: | Article |
| Language: | English |
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Universiti Putra Malaysia Press
2009
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| Online Access: | http://psasir.upm.edu.my/id/eprint/40551/1/Alkaloids%20from%20Piper%20nigrum%20and%20Piper%20betle.pdf |
| _version_ | 1796973762937094144 |
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| author | Lim, Chyi Meei Ee, Gwendoline Cheng Lian Rahmani, Mawardi Bong, Choon Fah Joseph |
| author_facet | Lim, Chyi Meei Ee, Gwendoline Cheng Lian Rahmani, Mawardi Bong, Choon Fah Joseph |
| author_sort | Lim, Chyi Meei |
| collection | UPM |
| description | An investigation, on the roots of Piper nigrum and the aerial parts of Piper betle, has yielded several alkaloids. The dried root sample of Piper nigrum was extracted using various solvents in increasing polarity. The dried aerial part of Piper betle was extracted using the Soxhlet extraction method. The alkaloids isolated were pellitorine(1), (E)-1-[3',4'- (Methylenedioxy)cinnamoyl]piperidine(2), piperine(3), piperolactam D(4), cepharadione A(5), and 2,4-tetradecadienoic acid isobutyl amide(6). These compounds were isolated using chromatographic methods, while the elucidation of the structures was carried out using MS, IR and NMR techniques. The extracts of Piper nigrum and Piper betle were also tested for cytotoxicity activities. This is the first report on (E)-1-[3',4'-(Methylenedioxy)cinnamoyl] piperidine(2) from Piper nigrum as a natural product. |
| first_indexed | 2024-03-06T08:47:24Z |
| format | Article |
| id | upm.eprints-40551 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:47:24Z |
| publishDate | 2009 |
| publisher | Universiti Putra Malaysia Press |
| record_format | dspace |
| spelling | upm.eprints-405512015-11-20T03:58:13Z http://psasir.upm.edu.my/id/eprint/40551/ Alkaloids from Piper nigrum and Piper betle Lim, Chyi Meei Ee, Gwendoline Cheng Lian Rahmani, Mawardi Bong, Choon Fah Joseph An investigation, on the roots of Piper nigrum and the aerial parts of Piper betle, has yielded several alkaloids. The dried root sample of Piper nigrum was extracted using various solvents in increasing polarity. The dried aerial part of Piper betle was extracted using the Soxhlet extraction method. The alkaloids isolated were pellitorine(1), (E)-1-[3',4'- (Methylenedioxy)cinnamoyl]piperidine(2), piperine(3), piperolactam D(4), cepharadione A(5), and 2,4-tetradecadienoic acid isobutyl amide(6). These compounds were isolated using chromatographic methods, while the elucidation of the structures was carried out using MS, IR and NMR techniques. The extracts of Piper nigrum and Piper betle were also tested for cytotoxicity activities. This is the first report on (E)-1-[3',4'-(Methylenedioxy)cinnamoyl] piperidine(2) from Piper nigrum as a natural product. Universiti Putra Malaysia Press 2009-01 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40551/1/Alkaloids%20from%20Piper%20nigrum%20and%20Piper%20betle.pdf Lim, Chyi Meei and Ee, Gwendoline Cheng Lian and Rahmani, Mawardi and Bong, Choon Fah Joseph (2009) Alkaloids from Piper nigrum and Piper betle. Pertanika Journal of Science & Technology, 17 (1). pp. 149-154. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2017%20%281%29%20Jan.%202009/18%2078-2008-C.M.Lim.pdf |
| spellingShingle | Lim, Chyi Meei Ee, Gwendoline Cheng Lian Rahmani, Mawardi Bong, Choon Fah Joseph Alkaloids from Piper nigrum and Piper betle |
| title | Alkaloids from Piper nigrum and Piper betle |
| title_full | Alkaloids from Piper nigrum and Piper betle |
| title_fullStr | Alkaloids from Piper nigrum and Piper betle |
| title_full_unstemmed | Alkaloids from Piper nigrum and Piper betle |
| title_short | Alkaloids from Piper nigrum and Piper betle |
| title_sort | alkaloids from piper nigrum and piper betle |
| url | http://psasir.upm.edu.my/id/eprint/40551/1/Alkaloids%20from%20Piper%20nigrum%20and%20Piper%20betle.pdf |
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