Dietary risk factors for colorectal adenomatous polyps: a mini review

At least 6 million deaths occurred worldwide are due to cancer and this figure is expected to rise to 15 millions by the year 2020. Colorectal cancer is among the most commonly occurring cancers both globally and in Malaysia. Numerous studies have shown significant relationships between various diet...

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Main Authors: Ramadas, Amutha, Kandiah, Mirnalini, Jabbar, F., Hambali, Zarida
Format: Article
Language:English
Published: Universiti Putra Malaysia Press 2010
Online Access:http://psasir.upm.edu.my/id/eprint/40580/1/Dietary%20Risk%20Factors%20for%20Colorectal%20Adenomatous%20Polyps%20A%20Mini%20Review.pdf
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author Ramadas, Amutha
Kandiah, Mirnalini
Jabbar, F.
Hambali, Zarida
author_facet Ramadas, Amutha
Kandiah, Mirnalini
Jabbar, F.
Hambali, Zarida
author_sort Ramadas, Amutha
collection UPM
description At least 6 million deaths occurred worldwide are due to cancer and this figure is expected to rise to 15 millions by the year 2020. Colorectal cancer is among the most commonly occurring cancers both globally and in Malaysia. Numerous studies have shown significant relationships between various dietary components and the risks for colorectal cancer. Meanwhile, several theories have been suggested as etiological explanations, one of which is the influence of dietary factors on the cell proliferation rate. A higher cell proliferation rate is statistically associated with increased risk of colorectal cancer. However, evidence of a significant relationship between diet and colorectal adenomas, a potential precursor for colorectal cancer, remains insufficient. Colorectal adenomas or polyps are vital in their relationship with colorectal cancers as almost 70% of all colorectal cancers are developed from these polyps. Studying the modifiable risk factors related to polyps will provide an opportunity for the prevention of colorectal cancer even before it develops. This paper reviews the available evidence linking dietary factors with the risk for colorectal adenomas. As the numbers of published studies are limited, of which most are concentrated in Western countries, there is a need for epidemiological studies in Malaysia to strengthen the evidence of a relationship between diet and colorectal adenomas.
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spelling upm.eprints-405802016-01-05T07:23:30Z http://psasir.upm.edu.my/id/eprint/40580/ Dietary risk factors for colorectal adenomatous polyps: a mini review Ramadas, Amutha Kandiah, Mirnalini Jabbar, F. Hambali, Zarida At least 6 million deaths occurred worldwide are due to cancer and this figure is expected to rise to 15 millions by the year 2020. Colorectal cancer is among the most commonly occurring cancers both globally and in Malaysia. Numerous studies have shown significant relationships between various dietary components and the risks for colorectal cancer. Meanwhile, several theories have been suggested as etiological explanations, one of which is the influence of dietary factors on the cell proliferation rate. A higher cell proliferation rate is statistically associated with increased risk of colorectal cancer. However, evidence of a significant relationship between diet and colorectal adenomas, a potential precursor for colorectal cancer, remains insufficient. Colorectal adenomas or polyps are vital in their relationship with colorectal cancers as almost 70% of all colorectal cancers are developed from these polyps. Studying the modifiable risk factors related to polyps will provide an opportunity for the prevention of colorectal cancer even before it develops. This paper reviews the available evidence linking dietary factors with the risk for colorectal adenomas. As the numbers of published studies are limited, of which most are concentrated in Western countries, there is a need for epidemiological studies in Malaysia to strengthen the evidence of a relationship between diet and colorectal adenomas. Universiti Putra Malaysia Press 2010-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40580/1/Dietary%20Risk%20Factors%20for%20Colorectal%20Adenomatous%20Polyps%20A%20Mini%20Review.pdf Ramadas, Amutha and Kandiah, Mirnalini and Jabbar, F. and Hambali, Zarida (2010) Dietary risk factors for colorectal adenomatous polyps: a mini review. Pertanika Journal of Science & Technology, 18 (2). pp. 321-349. ISSN 0128-7680; ESSN: 2231-8526 http://www.pertanika.upm.edu.my/Pertanika%20PAPERS/JST%20Vol.%2018%20%282%29%20Jul.%202010/13%20Pg%20321-350.pdf
spellingShingle Ramadas, Amutha
Kandiah, Mirnalini
Jabbar, F.
Hambali, Zarida
Dietary risk factors for colorectal adenomatous polyps: a mini review
title Dietary risk factors for colorectal adenomatous polyps: a mini review
title_full Dietary risk factors for colorectal adenomatous polyps: a mini review
title_fullStr Dietary risk factors for colorectal adenomatous polyps: a mini review
title_full_unstemmed Dietary risk factors for colorectal adenomatous polyps: a mini review
title_short Dietary risk factors for colorectal adenomatous polyps: a mini review
title_sort dietary risk factors for colorectal adenomatous polyps a mini review
url http://psasir.upm.edu.my/id/eprint/40580/1/Dietary%20Risk%20Factors%20for%20Colorectal%20Adenomatous%20Polyps%20A%20Mini%20Review.pdf
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