Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less
This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573...
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| Format: | Article |
| Language: | English |
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Faculty of Food Science and Technology, Universiti Putra Malaysia
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf |
| _version_ | 1796973788349333504 |
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| author | Ab. Rahim, Noridayu Hii, Yueh Feng Abas, Faridah Shaari, Khozirah Lajis, Nordin |
| author_facet | Ab. Rahim, Noridayu Hii, Yueh Feng Abas, Faridah Shaari, Khozirah Lajis, Nordin |
| author_sort | Ab. Rahim, Noridayu |
| collection | UPM |
| description | This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573.52 ± 6.2 mg GAE/100 g crude extract), in DPPH radical scavenging and Folin-Ciocalteu assays respectively, however, it failed to inhibit acetylcholinesterase in TLC bioautographic detection. The rest of plant extracts, included methanolic extract of stems, hexane extract of both leaves and stems, were detected to have acetylcholinesterase inhibitory properties. Hexane extract of both leaves and stems exhibited lower or negligible level of antioxidant activity and phenolic contents. Pluchea indica may provide a potential natural source of bioactive compounds, and maybe beneficial to the human health. |
| first_indexed | 2024-03-06T08:47:46Z |
| format | Article |
| id | upm.eprints-40678 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:47:46Z |
| publishDate | 2011 |
| publisher | Faculty of Food Science and Technology, Universiti Putra Malaysia |
| record_format | dspace |
| spelling | upm.eprints-406782015-11-27T02:52:22Z http://psasir.upm.edu.my/id/eprint/40678/ Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less Ab. Rahim, Noridayu Hii, Yueh Feng Abas, Faridah Shaari, Khozirah Lajis, Nordin This study was undertaken to evaluate the antioxidant and acetylcholinesterase inhibition properties of stems and leaf of hexane and methanolic extracts of Pluchea indica. Methanolic extract of leaves showed the highest antioxidant activity (IC50= 24.45 ± 0.34 μg/ml) and total phenolic contents (573.52 ± 6.2 mg GAE/100 g crude extract), in DPPH radical scavenging and Folin-Ciocalteu assays respectively, however, it failed to inhibit acetylcholinesterase in TLC bioautographic detection. The rest of plant extracts, included methanolic extract of stems, hexane extract of both leaves and stems, were detected to have acetylcholinesterase inhibitory properties. Hexane extract of both leaves and stems exhibited lower or negligible level of antioxidant activity and phenolic contents. Pluchea indica may provide a potential natural source of bioactive compounds, and maybe beneficial to the human health. Faculty of Food Science and Technology, Universiti Putra Malaysia 2011 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf Ab. Rahim, Noridayu and Hii, Yueh Feng and Abas, Faridah and Shaari, Khozirah and Lajis, Nordin (2011) Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less. International Food Research Journal, 18 (3). pp. 925-929. ISSN 1985-4668; ESSN: 2231-7546 http://www.ifrj.upm.edu.my/18%20%2803%29%202011/%2810%29IFRJ-2010-294.pdf |
| spellingShingle | Ab. Rahim, Noridayu Hii, Yueh Feng Abas, Faridah Shaari, Khozirah Lajis, Nordin Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title | Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title_full | Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title_fullStr | Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title_full_unstemmed | Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title_short | Antioxidant and antiacetylcholinesterase activities of Pluchea indica Less |
| title_sort | antioxidant and antiacetylcholinesterase activities of pluchea indica less |
| url | http://psasir.upm.edu.my/id/eprint/40678/1/Antioxidant%20and%20antiacetylcholinesterase%20activities%20of%20Pluchea%20indica%20Less..pdf |
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