Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs

The anaesthetic effects of intravenous administration oftiletamine (2.5 mg/kg) - zolazepam (2.5 mg/kg) mixture (TZ), and tiletamine (0.5 mglkg) - zolazepam (0.5 mg/kg) - ketamine (1.6 mg/kg) - xylazine (0.4 mg/kg) mixture (TKX) were evaluated in ten dogs. Atropine sulphate at a dose rate ofO.05 mg/k...

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Main Authors: Chen, Hui Cheng, Yeoh, H. Y., Yeoh, E. C.
Format: Article
Language:English
Published: Veterinary Association Malaysia 2005
Online Access:http://psasir.upm.edu.my/id/eprint/41522/1/0001.pdf
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author Chen, Hui Cheng
Yeoh, H. Y.
Yeoh, E. C.
author_facet Chen, Hui Cheng
Yeoh, H. Y.
Yeoh, E. C.
author_sort Chen, Hui Cheng
collection UPM
description The anaesthetic effects of intravenous administration oftiletamine (2.5 mg/kg) - zolazepam (2.5 mg/kg) mixture (TZ), and tiletamine (0.5 mglkg) - zolazepam (0.5 mg/kg) - ketamine (1.6 mg/kg) - xylazine (0.4 mg/kg) mixture (TKX) were evaluated in ten dogs. Atropine sulphate at a dose rate ofO.05 mg/kg was administered concurrently with the anaesthetic mixtures. Both mixtures produced rapid, smooth induction, and allowed intubation. The TKX mixture produced longer skin clamp analgesia and immobilisation, better jaw relaxation, with shorter and smoother recovery compared to TZ injection. The TKX mixture induced significant but transient pallor of mucous membranes « 2 min). The TZ mixture resulted in increased heart rate and a higher respiratory rate compared to TKX mixture. Haemoglobin saturation was < 90% in some dogs following either mixture. The TKX mixture can be considered as an alternative injectable mixture to TZ for short and minimally invasive procedures in patients that have no cardiopulmonary dysfunction.
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spelling upm.eprints-415222015-12-22T00:14:26Z http://psasir.upm.edu.my/id/eprint/41522/ Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs Chen, Hui Cheng Yeoh, H. Y. Yeoh, E. C. The anaesthetic effects of intravenous administration oftiletamine (2.5 mg/kg) - zolazepam (2.5 mg/kg) mixture (TZ), and tiletamine (0.5 mglkg) - zolazepam (0.5 mg/kg) - ketamine (1.6 mg/kg) - xylazine (0.4 mg/kg) mixture (TKX) were evaluated in ten dogs. Atropine sulphate at a dose rate ofO.05 mg/kg was administered concurrently with the anaesthetic mixtures. Both mixtures produced rapid, smooth induction, and allowed intubation. The TKX mixture produced longer skin clamp analgesia and immobilisation, better jaw relaxation, with shorter and smoother recovery compared to TZ injection. The TKX mixture induced significant but transient pallor of mucous membranes « 2 min). The TZ mixture resulted in increased heart rate and a higher respiratory rate compared to TKX mixture. Haemoglobin saturation was < 90% in some dogs following either mixture. The TKX mixture can be considered as an alternative injectable mixture to TZ for short and minimally invasive procedures in patients that have no cardiopulmonary dysfunction. Veterinary Association Malaysia 2005-07 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/41522/1/0001.pdf Chen, Hui Cheng and Yeoh, H. Y. and Yeoh, E. C. (2005) Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs. Jurnal Veterinar Malaysia, 17 (1). pp. 1-6. ISSN 9128-2506
spellingShingle Chen, Hui Cheng
Yeoh, H. Y.
Yeoh, E. C.
Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title_full Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title_fullStr Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title_full_unstemmed Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title_short Comparison of tiletamine-zolazepam and tiletamine-zolazepam-ketamine-xylazine administered intravenously in dogs
title_sort comparison of tiletamine zolazepam and tiletamine zolazepam ketamine xylazine administered intravenously in dogs
url http://psasir.upm.edu.my/id/eprint/41522/1/0001.pdf
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