Dissolution profiling and its comparison of natural fruit powder effervescent tablets

The aims of the study were to observe the dissolution profile of four types of selected fruit powder fast dissolve tablet and apply different dissolution profile comparison methods, in order to select most applicable method. Spray dried powder of pitaya, pineapple, guava and mango were used as raw m...

Full description

Bibliographic Details
Main Authors: Saifullah, M., Yusof, Yus Aniza, Chin, Nyuk Ling, Aziz, Mohammad Gulzarul, P. Mohammed, Mohd Afandi, Abdul Aziz, Norashikin
Format: Article
Language:English
Published: Elsevier 2016
Online Access:http://psasir.upm.edu.my/id/eprint/43205/1/Dissolution%20profiling%20and%20its%20comparison%20of%20natural%20fruit%20powder%20effervescent%20tablets.pdf
_version_ 1796974295391404032
author Saifullah, M.
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
P. Mohammed, Mohd Afandi
Abdul Aziz, Norashikin
author_facet Saifullah, M.
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
P. Mohammed, Mohd Afandi
Abdul Aziz, Norashikin
author_sort Saifullah, M.
collection UPM
description The aims of the study were to observe the dissolution profile of four types of selected fruit powder fast dissolve tablet and apply different dissolution profile comparison methods, in order to select most applicable method. Spray dried powder of pitaya, pineapple, guava and mango were used as raw material. Each type of fruit powder tablet has identical dissolution profile. Dissolution profiles and dissolution rate of fruit powder tablets were different at different dissolution environment. In model-independent and statistical method pairwise comparison was performed and in model dependent method profile comparison was carried out based on best fitting of mathematical model equation. Dissolution Profile comparison methods represented that model independent method use wide range of value for profile comparison and it was direct and easy; model dependent method was indirect and complex and for critically compare the dissolution profile statistical method was the most suitable method.
first_indexed 2024-03-06T08:54:58Z
format Article
id upm.eprints-43205
institution Universiti Putra Malaysia
language English
last_indexed 2024-03-06T08:54:58Z
publishDate 2016
publisher Elsevier
record_format dspace
spelling upm.eprints-432052016-05-18T04:11:39Z http://psasir.upm.edu.my/id/eprint/43205/ Dissolution profiling and its comparison of natural fruit powder effervescent tablets Saifullah, M. Yusof, Yus Aniza Chin, Nyuk Ling Aziz, Mohammad Gulzarul P. Mohammed, Mohd Afandi Abdul Aziz, Norashikin The aims of the study were to observe the dissolution profile of four types of selected fruit powder fast dissolve tablet and apply different dissolution profile comparison methods, in order to select most applicable method. Spray dried powder of pitaya, pineapple, guava and mango were used as raw material. Each type of fruit powder tablet has identical dissolution profile. Dissolution profiles and dissolution rate of fruit powder tablets were different at different dissolution environment. In model-independent and statistical method pairwise comparison was performed and in model dependent method profile comparison was carried out based on best fitting of mathematical model equation. Dissolution Profile comparison methods represented that model independent method use wide range of value for profile comparison and it was direct and easy; model dependent method was indirect and complex and for critically compare the dissolution profile statistical method was the most suitable method. Elsevier 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43205/1/Dissolution%20profiling%20and%20its%20comparison%20of%20natural%20fruit%20powder%20effervescent%20tablets.pdf Saifullah, M. and Yusof, Yus Aniza and Chin, Nyuk Ling and Aziz, Mohammad Gulzarul and P. Mohammed, Mohd Afandi and Abdul Aziz, Norashikin (2016) Dissolution profiling and its comparison of natural fruit powder effervescent tablets. Journal of Food Engineering, 178. pp. 60-70. ISSN 0260-8774; ESSN: 1873-5770 http://www.sciencedirect.com/science/article/pii/S0260877416300073 10.1016/j.jfoodeng.2016.01.007
spellingShingle Saifullah, M.
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
P. Mohammed, Mohd Afandi
Abdul Aziz, Norashikin
Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title_full Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title_fullStr Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title_full_unstemmed Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title_short Dissolution profiling and its comparison of natural fruit powder effervescent tablets
title_sort dissolution profiling and its comparison of natural fruit powder effervescent tablets
url http://psasir.upm.edu.my/id/eprint/43205/1/Dissolution%20profiling%20and%20its%20comparison%20of%20natural%20fruit%20powder%20effervescent%20tablets.pdf
work_keys_str_mv AT saifullahm dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets
AT yusofyusaniza dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets
AT chinnyukling dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets
AT azizmohammadgulzarul dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets
AT pmohammedmohdafandi dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets
AT abdulaziznorashikin dissolutionprofilinganditscomparisonofnaturalfruitpowdereffervescenttablets