The effects of propranolol and chlorisondamine on amphetamine hyperthermic action on brown adipose tissue in lean and obese zucker rats
Thermogenic capacity of brown adipose tissue was measured by [3H] GDP binding on the mitochondrial preparation of the tissue. Obese Zucker Rats are found to be more sensitive to amphetamine compared to the lean genotype. Amphetamine stimulation involves β - receptors and is centrally controlled. Inc...
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| Format: | Article |
| Language: | English |
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Malaysian Nuclear Agency
1989
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43383/1/The%20effects%20of%20propranolol%20and%20chlorisondamine.pdf |
| Summary: | Thermogenic capacity of brown adipose tissue was measured by [3H] GDP binding on the mitochondrial preparation of the tissue. Obese Zucker Rats are found to be more sensitive to amphetamine compared to the lean genotype. Amphetamine stimulation involves β - receptors and is centrally controlled. Increase in thermogenesis by amphetamine does not involve stimulation of the mitochondrial enzymic activity. |
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