Ultrasonic emulsification of parenteral valproic acid-loaded nanoemulsion with response surface methodology and evaluation of its stability
Response surface methodology (RSM) was used to optimize the formulation of a nanoemulsion for central delivery following parenteral administration. A mixture of medium-chain triglyceride (MCT) and safflower seed oil (SSO) was determined as a sole phase from the emulsification properties. Similarly,...
Main Authors: | Tan, Suk Fei, Masoumi, Hamid Reza Fard, Karjiban, Roghayeh Abedi, Stanslas, Johnson, Kirby, Brian P., Basri, Mahiran, Basri, Hamidon |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2016
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Online Access: | http://psasir.upm.edu.my/id/eprint/43429/1/Ultrasonic%20emulsification%20of%20parenteral%20valproic%20acid-loaded%20nanoemulsion%20with%20response%20surface%20methodology%20and%20evaluation%20of%20its%20stability.pdf |
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