A new coumarin from stem bark of Mesua hexapetala
A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (...
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| Format: | Article |
| Language: | English |
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Taylor & Francis
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43523/1/A%20new%20coumarin%20from%20stem%20bark%20of%20Mesua%20hexapetala.pdf |
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| author | Karunakaran, Thiruventhan Ee, Gwendoline Cheng Lian Teh, Soek Sin Daud, Shaari Mah, Siau Hui Lim, Chan Kiang Jong, Vivien Yi Mian Awang, Khalijah |
| author_facet | Karunakaran, Thiruventhan Ee, Gwendoline Cheng Lian Teh, Soek Sin Daud, Shaari Mah, Siau Hui Lim, Chan Kiang Jong, Vivien Yi Mian Awang, Khalijah |
| author_sort | Karunakaran, Thiruventhan |
| collection | UPM |
| description | A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity. |
| first_indexed | 2024-03-06T08:55:55Z |
| format | Article |
| id | upm.eprints-43523 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:55:55Z |
| publishDate | 2016 |
| publisher | Taylor & Francis |
| record_format | dspace |
| spelling | upm.eprints-435232016-11-30T01:13:59Z http://psasir.upm.edu.my/id/eprint/43523/ A new coumarin from stem bark of Mesua hexapetala Karunakaran, Thiruventhan Ee, Gwendoline Cheng Lian Teh, Soek Sin Daud, Shaari Mah, Siau Hui Lim, Chan Kiang Jong, Vivien Yi Mian Awang, Khalijah A new alkylated coumarin derivative, hexapetarin (1) along with three other xanthones, trapezifolixanthone (2), cudraxanthone G (3) and 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4), and four common triterpenoids, friedelin (5), stigmasterol (6), beta-sitosterol (7) and gamma-sitosterol (8) were isolated from the stem bark of Mesua hexapetala (Clusiaceae), a plant, native to Malaysia. The structures of these compounds were elucidated and determined using spectroscopic techniques such as NMR and MS. Anti-inflammatory activity assay indicated hexapetarin (1) to possess moderate anti-inflammatory activity, while 1,3,7-trihydroxy-2,4-di (3-methyl-2-butenyl)xanthone (4) gave very good activity. Taylor & Francis 2016-12-28 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43523/1/A%20new%20coumarin%20from%20stem%20bark%20of%20Mesua%20hexapetala.pdf Karunakaran, Thiruventhan and Ee, Gwendoline Cheng Lian and Teh, Soek Sin and Daud, Shaari and Mah, Siau Hui and Lim, Chan Kiang and Jong, Vivien Yi Mian and Awang, Khalijah (2016) A new coumarin from stem bark of Mesua hexapetala. Natural Product Research, 30 (14). pp. 1591-1597. ISSN 1478-6419; ESSN: 1478-6427 10.1080/14786419.2015.1120727 |
| spellingShingle | Karunakaran, Thiruventhan Ee, Gwendoline Cheng Lian Teh, Soek Sin Daud, Shaari Mah, Siau Hui Lim, Chan Kiang Jong, Vivien Yi Mian Awang, Khalijah A new coumarin from stem bark of Mesua hexapetala |
| title | A new coumarin from stem bark of Mesua hexapetala |
| title_full | A new coumarin from stem bark of Mesua hexapetala |
| title_fullStr | A new coumarin from stem bark of Mesua hexapetala |
| title_full_unstemmed | A new coumarin from stem bark of Mesua hexapetala |
| title_short | A new coumarin from stem bark of Mesua hexapetala |
| title_sort | new coumarin from stem bark of mesua hexapetala |
| url | http://psasir.upm.edu.my/id/eprint/43523/1/A%20new%20coumarin%20from%20stem%20bark%20of%20Mesua%20hexapetala.pdf |
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