Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats
The aim of this study was to evaluate the effects of fortification and nano-size reduction on calcium absorption and bioavailability of milk powder formula in sham, ovariectomized, and ovariectomized-osteoporosis rats as a menopause and menopause-osteoporosis model. Skim milk powder and skim milk po...
| Main Authors: | , , , , , |
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| Format: | Article |
| Language: | English |
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American Chemical Society
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43631/1/Absorption%20and%20bioavailability%20of%20nano-size%20reduced%20calcium%20citrate%20fortified%20milk%20powder%20in%20ovariectomized%20and%20ovariectomized-osteoporosis%20rats.pdf |
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| author | Erfanian, Arezoo Mirhosseini, Hamed Rasti, Babak Bejo, Mohd Hair Mustafa, Shuhaimi Abd Manap, Mohd Yazid |
| author_facet | Erfanian, Arezoo Mirhosseini, Hamed Rasti, Babak Bejo, Mohd Hair Mustafa, Shuhaimi Abd Manap, Mohd Yazid |
| author_sort | Erfanian, Arezoo |
| collection | UPM |
| description | The aim of this study was to evaluate the effects of fortification and nano-size reduction on calcium absorption and bioavailability of milk powder formula in sham, ovariectomized, and ovariectomized-osteoporosis rats as a menopause and menopause-osteoporosis model. Skim milk powder and skim milk powder fortified with calcium citrate and the suitable doses of inulin, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and vitamins D3, K1, and B6 were formulated based on the North American and Western European recommended dietary allowances. Optimization on cycle and pressure of high-pressure homogenizer was done to produce nano-fortified milk powder. In vivo study demonstrated that fortification and calcium citrate nano-fortified milk powder increased absorption and bioavailability of calcium, as well as bone stiffness and bone strength in sham, ovariectomized, and ovariectomized-osteoporosis rats. This study successfully developed an effective fortified milk powder for food application. |
| first_indexed | 2024-03-06T08:56:14Z |
| format | Article |
| id | upm.eprints-43631 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:56:14Z |
| publishDate | 2015 |
| publisher | American Chemical Society |
| record_format | dspace |
| spelling | upm.eprints-436312016-07-22T02:33:03Z http://psasir.upm.edu.my/id/eprint/43631/ Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats Erfanian, Arezoo Mirhosseini, Hamed Rasti, Babak Bejo, Mohd Hair Mustafa, Shuhaimi Abd Manap, Mohd Yazid The aim of this study was to evaluate the effects of fortification and nano-size reduction on calcium absorption and bioavailability of milk powder formula in sham, ovariectomized, and ovariectomized-osteoporosis rats as a menopause and menopause-osteoporosis model. Skim milk powder and skim milk powder fortified with calcium citrate and the suitable doses of inulin, eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA), and vitamins D3, K1, and B6 were formulated based on the North American and Western European recommended dietary allowances. Optimization on cycle and pressure of high-pressure homogenizer was done to produce nano-fortified milk powder. In vivo study demonstrated that fortification and calcium citrate nano-fortified milk powder increased absorption and bioavailability of calcium, as well as bone stiffness and bone strength in sham, ovariectomized, and ovariectomized-osteoporosis rats. This study successfully developed an effective fortified milk powder for food application. American Chemical Society 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/43631/1/Absorption%20and%20bioavailability%20of%20nano-size%20reduced%20calcium%20citrate%20fortified%20milk%20powder%20in%20ovariectomized%20and%20ovariectomized-osteoporosis%20rats.pdf Erfanian, Arezoo and Mirhosseini, Hamed and Rasti, Babak and Bejo, Mohd Hair and Mustafa, Shuhaimi and Abd Manap, Mohd Yazid (2015) Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats. Journal of Agricultural and Food Chemistry, 63 (24). pp. 5795-5804. ISSN 0021-8561 http://pubs.acs.org/doi/abs/10.1021/acs.jafc.5b01468 10.1021/acs.jafc.5b01468 |
| spellingShingle | Erfanian, Arezoo Mirhosseini, Hamed Rasti, Babak Bejo, Mohd Hair Mustafa, Shuhaimi Abd Manap, Mohd Yazid Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title | Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title_full | Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title_fullStr | Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title_full_unstemmed | Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title_short | Absorption and bioavailability of nano-size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized-osteoporosis rats |
| title_sort | absorption and bioavailability of nano size reduced calcium citrate fortified milk powder in ovariectomized and ovariectomized osteoporosis rats |
| url | http://psasir.upm.edu.my/id/eprint/43631/1/Absorption%20and%20bioavailability%20of%20nano-size%20reduced%20calcium%20citrate%20fortified%20milk%20powder%20in%20ovariectomized%20and%20ovariectomized-osteoporosis%20rats.pdf |
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