Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms
Aims: The aim of the study was to investigate the antimicrobial activity of Nauclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and matured trees of N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process....
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| Format: | Article |
| Language: | English |
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Malaysian Society for Microbiology
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/43794/1/Antimicrobial%20activities%20of%20stembark%20and%20wood%20extracts%20from%20Nauclea%20subdita%20against%20.pdf |
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| author | Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin |
| author_facet | Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin |
| author_sort | Jamaluddin, Fatin Ruzanna |
| collection | UPM |
| description | Aims: The aim of the study was to investigate the antimicrobial activity of Nauclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and matured trees of N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 μg/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications. |
| first_indexed | 2024-03-06T08:56:43Z |
| format | Article |
| id | upm.eprints-43794 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:56:43Z |
| publishDate | 2015 |
| publisher | Malaysian Society for Microbiology |
| record_format | dspace |
| spelling | upm.eprints-437942018-04-09T06:22:51Z http://psasir.upm.edu.my/id/eprint/43794/ Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin Aims: The aim of the study was to investigate the antimicrobial activity of Nauclea subdita (Korth) Steud against six pathogenic microorganisms. Methodology and results: Young and matured trees of N. subdita were cut and separated into bark and wood parts, respectively, prior to extraction process. Phytochemical screening tests, antimicrobial activity, minimal inhibitory concentration (MIC) and minimal bactericidal concentration (MBC) values were determined. Preliminary screening for phytochemical components showed that both young and matured tree had similar constituents. Extracts from matured tree showed more potency in terms of the zones of inhibition sizes than the young tree. Extract of N. subdita was more potent to both marine bacteria, Vibrio parahaemoliticus and V. alginolyticus, while Candida albican and Aspergillus niger were resistant to it. The sensitivity test showed that 500 μg/mL is the optimum concentration for extract of bottom sapwood of mature tree to act as bactericidal. Conclusion, significance and impact study: The results from this study suggest that N. subdita bark and wood extracts may serve as potential source of antimicrobial agents for future development in medicine applications. Malaysian Society for Microbiology 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/43794/1/Antimicrobial%20activities%20of%20stembark%20and%20wood%20extracts%20from%20Nauclea%20subdita%20against%20.pdf Jamaluddin, Fatin Ruzanna and Lee, Seng Hua and Ashaari, Zaidon and Wahab, Razak and Mohd Daud, Jamaluddin (2015) Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms. Malaysian Journal of Microbiology, 11 (4). pp. 365-372. ISSN 1823-8262; ESSN: 2231-7538 |
| spellingShingle | Jamaluddin, Fatin Ruzanna Lee, Seng Hua Ashaari, Zaidon Wahab, Razak Mohd Daud, Jamaluddin Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title | Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title_full | Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title_fullStr | Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title_full_unstemmed | Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title_short | Antimicrobial activities of stembark and wood extracts from Nauclea subdita against pathogenic microorganisms |
| title_sort | antimicrobial activities of stembark and wood extracts from nauclea subdita against pathogenic microorganisms |
| url | http://psasir.upm.edu.my/id/eprint/43794/1/Antimicrobial%20activities%20of%20stembark%20and%20wood%20extracts%20from%20Nauclea%20subdita%20against%20.pdf |
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