Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae)
There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian spe...
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| Format: | Conference or Workshop Item |
| Language: | English |
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IEEE
2011
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| Online Access: | http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf |
| _version_ | 1825929560024154112 |
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| author | Khong, Heng Yen Jong, Vivien Yi Mian Ee, Gwendoline Cheng Lian |
| author_facet | Khong, Heng Yen Jong, Vivien Yi Mian Ee, Gwendoline Cheng Lian |
| author_sort | Khong, Heng Yen |
| collection | UPM |
| description | There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian species which are Garcinia eugenifolia and Garcinia nitida which have not been reported before. The methanol extract from the G. eugenifolia leaves exhibited moderate antioxidant activity with EC50 values of 66 and 51 respectively, when compared to ascorbic acid with EC50 values of 15.32 μg/mL. This crude also showed weak cytotoxic activity to HeLa with IC50 values of 71 and 40 μg/mL respectively. However, the leaves extracts of G. nitida showed good cytotoxic activity with IC50 values of 4 and 7 μg/mL respectively towards both cell lines. |
| first_indexed | 2024-03-06T08:58:31Z |
| format | Conference or Workshop Item |
| id | upm.eprints-45286 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:58:31Z |
| publishDate | 2011 |
| publisher | IEEE |
| record_format | dspace |
| spelling | upm.eprints-452862020-08-05T06:48:13Z http://psasir.upm.edu.my/id/eprint/45286/ Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) Khong, Heng Yen Jong, Vivien Yi Mian Ee, Gwendoline Cheng Lian There are several local Malaysian Garcinia species which have ethnobotanical uses but so far very few studies have been carried out to link these folkloric uses with the phytochemistry of these plant species. It would be interesting therefore, to develop phytochemical data of two such Sarawakian species which are Garcinia eugenifolia and Garcinia nitida which have not been reported before. The methanol extract from the G. eugenifolia leaves exhibited moderate antioxidant activity with EC50 values of 66 and 51 respectively, when compared to ascorbic acid with EC50 values of 15.32 μg/mL. This crude also showed weak cytotoxic activity to HeLa with IC50 values of 71 and 40 μg/mL respectively. However, the leaves extracts of G. nitida showed good cytotoxic activity with IC50 values of 4 and 7 μg/mL respectively towards both cell lines. IEEE 2011 Conference or Workshop Item PeerReviewed text en http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf Khong, Heng Yen and Jong, Vivien Yi Mian and Ee, Gwendoline Cheng Lian (2011) Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae). In: 2011 IEEE Colloquium on Humanities, Science and Engineering (CHUSER 2011), 5-6 Dec. 2011, Penang, Malaysia. (pp. 831-833). 10.1109/CHUSER.2011.6163853 |
| spellingShingle | Khong, Heng Yen Jong, Vivien Yi Mian Ee, Gwendoline Cheng Lian Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title | Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title_full | Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title_fullStr | Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title_full_unstemmed | Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title_short | Cytotoxic and antioxidant properties of Borneo Garcinia species (Clusiaceae) |
| title_sort | cytotoxic and antioxidant properties of borneo garcinia species clusiaceae |
| url | http://psasir.upm.edu.my/id/eprint/45286/1/Cytotoxic%20and%20antioxidant%20properties%20of%20Borneo%20Garcinia%20species%20%28Clusiaceae%29.pdf |
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