Label and label-free detection techniques for protein microarrays
Protein microarray technology has gone through numerous innovative developments in recent decades. In this review, we focus on the development of protein detection methods embedded in the technology. Early microarrays utilized useful chromophores and versatile biochemical techniques dominated by hig...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
| Published: |
Multidisciplinary Digital Publishing Institute
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/45304/1/PROTEIN.pdf |
| _version_ | 1796974539856412672 |
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| author | Amir Hamzah, Amir Syahir Usui, Kenji Tomizaki, Kinya Kajikawa, Kotaro Mihara, Hisakazu |
| author_facet | Amir Hamzah, Amir Syahir Usui, Kenji Tomizaki, Kinya Kajikawa, Kotaro Mihara, Hisakazu |
| author_sort | Amir Hamzah, Amir Syahir |
| collection | UPM |
| description | Protein microarray technology has gone through numerous innovative developments in recent decades. In this review, we focus on the development of protein detection methods embedded in the technology. Early microarrays utilized useful chromophores and versatile biochemical techniques dominated by high-throughput illumination. Recently, the realization of label-free techniques has been greatly advanced by the combination of knowledge in material sciences, computational design and nanofabrication. These rapidly advancing techniques aim to provide data without the intervention of label molecules. Here, we present a brief overview of this remarkable innovation from the perspectives of label and label-free techniques in transducing nano-biological events. |
| first_indexed | 2024-03-06T08:58:31Z |
| format | Article |
| id | upm.eprints-45304 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:58:31Z |
| publishDate | 2015 |
| publisher | Multidisciplinary Digital Publishing Institute |
| record_format | dspace |
| spelling | upm.eprints-453042021-04-18T01:46:10Z http://psasir.upm.edu.my/id/eprint/45304/ Label and label-free detection techniques for protein microarrays Amir Hamzah, Amir Syahir Usui, Kenji Tomizaki, Kinya Kajikawa, Kotaro Mihara, Hisakazu Protein microarray technology has gone through numerous innovative developments in recent decades. In this review, we focus on the development of protein detection methods embedded in the technology. Early microarrays utilized useful chromophores and versatile biochemical techniques dominated by high-throughput illumination. Recently, the realization of label-free techniques has been greatly advanced by the combination of knowledge in material sciences, computational design and nanofabrication. These rapidly advancing techniques aim to provide data without the intervention of label molecules. Here, we present a brief overview of this remarkable innovation from the perspectives of label and label-free techniques in transducing nano-biological events. Multidisciplinary Digital Publishing Institute 2015-06 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/45304/1/PROTEIN.pdf Amir Hamzah, Amir Syahir and Usui, Kenji and Tomizaki, Kinya and Kajikawa, Kotaro and Mihara, Hisakazu (2015) Label and label-free detection techniques for protein microarrays. Microarrays, 4 (2). pp. 228-244. ISSN 2076-3905 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4996399/ 10.3390/microarrays4020228 |
| spellingShingle | Amir Hamzah, Amir Syahir Usui, Kenji Tomizaki, Kinya Kajikawa, Kotaro Mihara, Hisakazu Label and label-free detection techniques for protein microarrays |
| title | Label and label-free detection techniques for protein microarrays |
| title_full | Label and label-free detection techniques for protein microarrays |
| title_fullStr | Label and label-free detection techniques for protein microarrays |
| title_full_unstemmed | Label and label-free detection techniques for protein microarrays |
| title_short | Label and label-free detection techniques for protein microarrays |
| title_sort | label and label free detection techniques for protein microarrays |
| url | http://psasir.upm.edu.my/id/eprint/45304/1/PROTEIN.pdf |
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