Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression
As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibit...
| Main Authors: | , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , , |
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| Format: | Article |
| Language: | English |
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Oxford University Press
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/45440/1/DNA.pdf |
| _version_ | 1825929571436855296 |
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| author | Nahta, Rita Al-Mulla, Fahd Al-Temaimi, Rabeah Amedei, Amedeo Andrade Vieira, Rafaela Bay, Sarah N. Brown, Dustin G. Calaf, Gloria M. Castellino, Robert C. Cohen Solal, Karine A. Colacci, Anna Maria Cruickshanks, Nichola Dent, Paul Di Fiore, Riccardo Forte, Stefano Goldberg, Gary S. A. Hamid, Roslida Krishnan, Harini Laird, Dale W. Lasfar, Ahmed Marignani, Paola A. Memeo, Lorenzo Mondello, Chiara Naus, Christian C. Ponce Cusi, Richard Raju, Jayadev Roy, Debasish Roy, Rabindra Ryan, Elizabeth P. Salem, Hosni K. Scovassi, A. Ivana Singh, Neetu Vaccari, Monica Vento, Renza Vondrá ček, Jan Wade, Mark Woodrick, Jordan Bisson, William H. |
| author_facet | Nahta, Rita Al-Mulla, Fahd Al-Temaimi, Rabeah Amedei, Amedeo Andrade Vieira, Rafaela Bay, Sarah N. Brown, Dustin G. Calaf, Gloria M. Castellino, Robert C. Cohen Solal, Karine A. Colacci, Anna Maria Cruickshanks, Nichola Dent, Paul Di Fiore, Riccardo Forte, Stefano Goldberg, Gary S. A. Hamid, Roslida Krishnan, Harini Laird, Dale W. Lasfar, Ahmed Marignani, Paola A. Memeo, Lorenzo Mondello, Chiara Naus, Christian C. Ponce Cusi, Richard Raju, Jayadev Roy, Debasish Roy, Rabindra Ryan, Elizabeth P. Salem, Hosni K. Scovassi, A. Ivana Singh, Neetu Vaccari, Monica Vento, Renza Vondrá ček, Jan Wade, Mark Woodrick, Jordan Bisson, William H. |
| author_sort | Nahta, Rita |
| collection | UPM |
| description | As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks. |
| first_indexed | 2024-03-06T08:58:41Z |
| format | Article |
| id | upm.eprints-45440 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:58:41Z |
| publishDate | 2015 |
| publisher | Oxford University Press |
| record_format | dspace |
| spelling | upm.eprints-454402021-05-06T23:28:16Z http://psasir.upm.edu.my/id/eprint/45440/ Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression Nahta, Rita Al-Mulla, Fahd Al-Temaimi, Rabeah Amedei, Amedeo Andrade Vieira, Rafaela Bay, Sarah N. Brown, Dustin G. Calaf, Gloria M. Castellino, Robert C. Cohen Solal, Karine A. Colacci, Anna Maria Cruickshanks, Nichola Dent, Paul Di Fiore, Riccardo Forte, Stefano Goldberg, Gary S. A. Hamid, Roslida Krishnan, Harini Laird, Dale W. Lasfar, Ahmed Marignani, Paola A. Memeo, Lorenzo Mondello, Chiara Naus, Christian C. Ponce Cusi, Richard Raju, Jayadev Roy, Debasish Roy, Rabindra Ryan, Elizabeth P. Salem, Hosni K. Scovassi, A. Ivana Singh, Neetu Vaccari, Monica Vento, Renza Vondrá ček, Jan Wade, Mark Woodrick, Jordan Bisson, William H. As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks. Oxford University Press 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/45440/1/DNA.pdf Nahta, Rita and Al-Mulla, Fahd and Al-Temaimi, Rabeah and Amedei, Amedeo and Andrade Vieira, Rafaela and Bay, Sarah N. and Brown, Dustin G. and Calaf, Gloria M. and Castellino, Robert C. and Cohen Solal, Karine A. and Colacci, Anna Maria and Cruickshanks, Nichola and Dent, Paul and Di Fiore, Riccardo and Forte, Stefano and Goldberg, Gary S. and A. Hamid, Roslida and Krishnan, Harini and Laird, Dale W. and Lasfar, Ahmed and Marignani, Paola A. and Memeo, Lorenzo and Mondello, Chiara and Naus, Christian C. and Ponce Cusi, Richard and Raju, Jayadev and Roy, Debasish and Roy, Rabindra and Ryan, Elizabeth P. and Salem, Hosni K. and Scovassi, A. Ivana and Singh, Neetu and Vaccari, Monica and Vento, Renza and Vondrá ček, Jan and Wade, Mark and Woodrick, Jordan and Bisson, William H. (2015) Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis, 36 (suppl. 1). pp. 2-18. ISSN 0143-3334; ESSN: 1460-2180 https://pubmed.ncbi.nlm.nih.gov/26106139/ 10.1093/carcin/bgv028 |
| spellingShingle | Nahta, Rita Al-Mulla, Fahd Al-Temaimi, Rabeah Amedei, Amedeo Andrade Vieira, Rafaela Bay, Sarah N. Brown, Dustin G. Calaf, Gloria M. Castellino, Robert C. Cohen Solal, Karine A. Colacci, Anna Maria Cruickshanks, Nichola Dent, Paul Di Fiore, Riccardo Forte, Stefano Goldberg, Gary S. A. Hamid, Roslida Krishnan, Harini Laird, Dale W. Lasfar, Ahmed Marignani, Paola A. Memeo, Lorenzo Mondello, Chiara Naus, Christian C. Ponce Cusi, Richard Raju, Jayadev Roy, Debasish Roy, Rabindra Ryan, Elizabeth P. Salem, Hosni K. Scovassi, A. Ivana Singh, Neetu Vaccari, Monica Vento, Renza Vondrá ček, Jan Wade, Mark Woodrick, Jordan Bisson, William H. Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title_full | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title_fullStr | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title_full_unstemmed | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title_short | Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| title_sort | mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression |
| url | http://psasir.upm.edu.my/id/eprint/45440/1/DNA.pdf |
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