Naturally-occurring glucosinolates, glucoraphanin and glucoerucin, are antagonists to aryl hydrocarbon receptor as their chemopreventive potency
As a cytosolic transcription factor, the aryl hydrocarbon (Ah) receptor is involved in several patho- physiological events leading to immunosuppression and cancer; hence antagonists of the Ah receptor may possess chemoprevention properties. It is known to modulate carcinogen-metabolising enzymes, fo...
Main Authors: | Abdull Razis, Ahmad Faizal, Mohd Noor, Noramaliza |
---|---|
Format: | Article |
Language: | English |
Published: |
Asian Pacific Organization for Cancer Prevention
2015
|
Online Access: | http://psasir.upm.edu.my/id/eprint/45581/1/AR.pdf |
Similar Items
-
Apoptosis as a mechanism of the cancer chemopreventive activity of glucosinolates: a review
by: Abdull Razis, Ahmad Faizal, et al.
Published: (2018) -
Sulforaphane is superior than glucoraphanin in modulating carcinogen-metabolising enzymes in Hep G2 cells
by: Abdull Razis, Ahmad Faizal, et al.
Published: (2013) -
Glucosinolates and isothiocyanates: cancer preventive effects
by: Abdull Razis, Ahmad Faizal, et al.
Published: (2017) -
The induction of aryl hydrocarbon receptor (AHR) in immune organs of developing chicks by polycyclic aromatic hydrocarbons
by: Nisha, A. R., et al.
Published: (2018) -
Comparative analyses of aryl hydrocarbon receptor structure, function, and evolution in marine mammals
by: Lapseritis, Joy M
Published: (2007)