Rapid ferritin iron release using FMN reductase
Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflamma...
| Main Authors: | , , , , |
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| Format: | Article |
| Language: | English |
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International Academy Publishing
2015
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| Online Access: | http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf |
| _version_ | 1825929636527210496 |
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| author | Lai, Mei I. Lim, Wai Feng Yap, Boon Kar George, Elizabeth Abdullah, Maha |
| author_facet | Lai, Mei I. Lim, Wai Feng Yap, Boon Kar George, Elizabeth Abdullah, Maha |
| author_sort | Lai, Mei I. |
| collection | UPM |
| description | Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflammation which does not affect the iron level that is available in the ferritin cage. Therefore, we designed a novel assay to achieve rapid ferritin iron release for the detection of iron deficiency anaemia using various biochemical compounds including reducing agents, oxygen scavenger compounds and chaotropic agents. |
| first_indexed | 2024-03-06T08:59:37Z |
| format | Article |
| id | upm.eprints-46079 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T08:59:37Z |
| publishDate | 2015 |
| publisher | International Academy Publishing |
| record_format | dspace |
| spelling | upm.eprints-460792022-03-23T06:24:23Z http://psasir.upm.edu.my/id/eprint/46079/ Rapid ferritin iron release using FMN reductase Lai, Mei I. Lim, Wai Feng Yap, Boon Kar George, Elizabeth Abdullah, Maha Iron deficiency anaemia is very common in developing countries and affects approximately two billion people worldwide. To test for iron deficiency, the common practice is to detect the body’s ferritin level using an automated machine. However, ferritin level can be confounded by inflammation which does not affect the iron level that is available in the ferritin cage. Therefore, we designed a novel assay to achieve rapid ferritin iron release for the detection of iron deficiency anaemia using various biochemical compounds including reducing agents, oxygen scavenger compounds and chaotropic agents. International Academy Publishing 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf Lai, Mei I. and Lim, Wai Feng and Yap, Boon Kar and George, Elizabeth and Abdullah, Maha (2015) Rapid ferritin iron release using FMN reductase. International Journal of Bioscience, Biochemistry and Bioinformatics, 5 (2). pp. 111-119. ISSN 2010-3638 http://www.ijbbb.org/show-56-742-1.html 10.17706/ijbbb.2015.5.2.111-119 |
| spellingShingle | Lai, Mei I. Lim, Wai Feng Yap, Boon Kar George, Elizabeth Abdullah, Maha Rapid ferritin iron release using FMN reductase |
| title | Rapid ferritin iron release using FMN reductase |
| title_full | Rapid ferritin iron release using FMN reductase |
| title_fullStr | Rapid ferritin iron release using FMN reductase |
| title_full_unstemmed | Rapid ferritin iron release using FMN reductase |
| title_short | Rapid ferritin iron release using FMN reductase |
| title_sort | rapid ferritin iron release using fmn reductase |
| url | http://psasir.upm.edu.my/id/eprint/46079/1/Rapid%20ferritin%20iron%20release%20using%20FMN%20reductase.pdf |
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