Recent advances in food biopeptides: production, biological functionalities and threapeutic applications

The growing momentum of several common life-style diseases such as myocardial infarction, cardiovascular disorders, stroke, hypertension, diabetes, and atherosclerosis has become a serious global concern. Recent developments in the field of proteomics offering promising solutions to solving such hea...

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Main Authors: Saadi, Sami, Saari, Nazamid, Anwar, Farooq, Abdul Hamid, Azizah, Mohd Ghazali, Hasanah
Format: Article
Language:English
Published: Elsevier 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46090/1/Recent%20advances%20in%20food%20biopeptides%20production%2C%20biological%20functionalities%20and%20threapeutic%20applications.pdf
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author Saadi, Sami
Saari, Nazamid
Anwar, Farooq
Abdul Hamid, Azizah
Mohd Ghazali, Hasanah
author_facet Saadi, Sami
Saari, Nazamid
Anwar, Farooq
Abdul Hamid, Azizah
Mohd Ghazali, Hasanah
author_sort Saadi, Sami
collection UPM
description The growing momentum of several common life-style diseases such as myocardial infarction, cardiovascular disorders, stroke, hypertension, diabetes, and atherosclerosis has become a serious global concern. Recent developments in the field of proteomics offering promising solutions to solving such health problems stimulates the uses of biopeptides as one of the therapeutic agents to alleviate disease-related risk factors. Functional peptides are typically produced from protein via enzymatic hydrolysis under in vitro or in vivo conditions using different kinds of proteolytic enzymes. An array of biological activities, including antioxidative, antihypertensive, antidiabetic and immunomodulating has been ascribed to different types of biopeptides derived from various food sources. In fact, biopeptides are nutritionally and functionally important for regulating some physiological functions in the body; however, these are yet to be extensively addressed with regard to their production through advance strategies, mechanisms of action and multiple biological functionalities. This review mainly focuses on recent biotechnological advances that are being made in the field of production in addition to covering the mode of action and biological activities, medicinal health functions and therapeutic applications of biopeptides. State-of-the-art strategies that can ameliorate the efficacy, bioavailability, and functionality of biopeptides along with their future prospects are likewise discussed.
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spelling upm.eprints-460902018-05-07T02:49:47Z http://psasir.upm.edu.my/id/eprint/46090/ Recent advances in food biopeptides: production, biological functionalities and threapeutic applications Saadi, Sami Saari, Nazamid Anwar, Farooq Abdul Hamid, Azizah Mohd Ghazali, Hasanah The growing momentum of several common life-style diseases such as myocardial infarction, cardiovascular disorders, stroke, hypertension, diabetes, and atherosclerosis has become a serious global concern. Recent developments in the field of proteomics offering promising solutions to solving such health problems stimulates the uses of biopeptides as one of the therapeutic agents to alleviate disease-related risk factors. Functional peptides are typically produced from protein via enzymatic hydrolysis under in vitro or in vivo conditions using different kinds of proteolytic enzymes. An array of biological activities, including antioxidative, antihypertensive, antidiabetic and immunomodulating has been ascribed to different types of biopeptides derived from various food sources. In fact, biopeptides are nutritionally and functionally important for regulating some physiological functions in the body; however, these are yet to be extensively addressed with regard to their production through advance strategies, mechanisms of action and multiple biological functionalities. This review mainly focuses on recent biotechnological advances that are being made in the field of production in addition to covering the mode of action and biological activities, medicinal health functions and therapeutic applications of biopeptides. State-of-the-art strategies that can ameliorate the efficacy, bioavailability, and functionality of biopeptides along with their future prospects are likewise discussed. Elsevier 2015 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/46090/1/Recent%20advances%20in%20food%20biopeptides%20production%2C%20biological%20functionalities%20and%20threapeutic%20applications.pdf Saadi, Sami and Saari, Nazamid and Anwar, Farooq and Abdul Hamid, Azizah and Mohd Ghazali, Hasanah (2015) Recent advances in food biopeptides: production, biological functionalities and threapeutic applications. Biotechnology Advances, 33 (1). pp. 80-116. ISSN 0734-9750; ESSN: 1873-1899 http://www.elsevier.com/locate/biotechadv 10.1016/j.biotechadv.2014.12.003
spellingShingle Saadi, Sami
Saari, Nazamid
Anwar, Farooq
Abdul Hamid, Azizah
Mohd Ghazali, Hasanah
Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title_full Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title_fullStr Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title_full_unstemmed Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title_short Recent advances in food biopeptides: production, biological functionalities and threapeutic applications
title_sort recent advances in food biopeptides production biological functionalities and threapeutic applications
url http://psasir.upm.edu.my/id/eprint/46090/1/Recent%20advances%20in%20food%20biopeptides%20production%2C%20biological%20functionalities%20and%20threapeutic%20applications.pdf
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