Synthesis of anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell lines

Synthesis of anthraquinone derivative (DHAQC) and its effect on induction of G2/M arrest and apoptosis in breast cancer MCF-7 cell lines

Anthraquinones are an important class of naturally occurring biologically active compounds. In this study, anthraquinone derivative 1,3-dihydroxy-9,10-anthraquinone-2- carboxylic acid (DHAQC) (2) was synthesized with 32% yield through the Friedel-Crafts condensation reaction. The mechanisms of cytot...

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Bibliographic Details
Main Authors:	Yeap, Swee Keong, Akhtar, Muhammad Nadeem, Kian, Lam Lim, Abu, Nadiah, Wan, Yong Ho, Zareen, Seema, Roohani, Kiarash, Huynh, Ky, Sheau, Wei Tan, Lajis, Md. Nordin, Mohamed Alitheen, Noorjahan Banu
Format:	Article
Language:	English
Published:	Dove Medical Press 2015
Online Access:	http://psasir.upm.edu.my/id/eprint/46467/1/Synthesis%20of%20anthraquinone%20derivative%20%28DHAQC%29%20and%20its%20effect%20on%20induction%20of%20G2M%20arrest%20and%20apoptosis%20in%20breast%20cancer%20MCF-7%20cell%20lines.pdf

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