Validation of a modified algometer to measure nociceptive thresholds in awake dogs
This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thres...
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Format: | Article |
Language: | English |
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Hindawi Publishing Corporation
2015
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Online Access: | http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf |
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author | Kaka, Ubedullah Hui, Cheng Chen Yong, Meng Goh Abdul Abubakar, Adamu Fakurazi, Sharida Ebrahimi, Mahdi |
author_facet | Kaka, Ubedullah Hui, Cheng Chen Yong, Meng Goh Abdul Abubakar, Adamu Fakurazi, Sharida Ebrahimi, Mahdi |
author_sort | Kaka, Ubedullah |
collection | UPM |
description | This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly ( |
first_indexed | 2024-03-06T09:01:21Z |
format | Article |
id | upm.eprints-46847 |
institution | Universiti Putra Malaysia |
language | English |
last_indexed | 2024-03-06T09:01:21Z |
publishDate | 2015 |
publisher | Hindawi Publishing Corporation |
record_format | dspace |
spelling | upm.eprints-468472018-01-31T06:57:24Z http://psasir.upm.edu.my/id/eprint/46847/ Validation of a modified algometer to measure nociceptive thresholds in awake dogs Kaka, Ubedullah Hui, Cheng Chen Yong, Meng Goh Abdul Abubakar, Adamu Fakurazi, Sharida Ebrahimi, Mahdi This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly ( Hindawi Publishing Corporation 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf Kaka, Ubedullah and Hui, Cheng Chen and Yong, Meng Goh and Abdul Abubakar, Adamu and Fakurazi, Sharida and Ebrahimi, Mahdi (2015) Validation of a modified algometer to measure nociceptive thresholds in awake dogs. BioMed Research International. art. no. 375421. pp. 1-7. ISSN 2314-6133; ESSN: 2314-6141 10.1155/2015/375421 |
spellingShingle | Kaka, Ubedullah Hui, Cheng Chen Yong, Meng Goh Abdul Abubakar, Adamu Fakurazi, Sharida Ebrahimi, Mahdi Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title | Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title_full | Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title_fullStr | Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title_full_unstemmed | Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title_short | Validation of a modified algometer to measure nociceptive thresholds in awake dogs |
title_sort | validation of a modified algometer to measure nociceptive thresholds in awake dogs |
url | http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf |
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