Validation of a modified algometer to measure nociceptive thresholds in awake dogs

This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thres...

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Main Authors: Kaka, Ubedullah, Hui, Cheng Chen, Yong, Meng Goh, Abdul Abubakar, Adamu, Fakurazi, Sharida, Ebrahimi, Mahdi
Format: Article
Language:English
Published: Hindawi Publishing Corporation 2015
Online Access:http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf
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author Kaka, Ubedullah
Hui, Cheng Chen
Yong, Meng Goh
Abdul Abubakar, Adamu
Fakurazi, Sharida
Ebrahimi, Mahdi
author_facet Kaka, Ubedullah
Hui, Cheng Chen
Yong, Meng Goh
Abdul Abubakar, Adamu
Fakurazi, Sharida
Ebrahimi, Mahdi
author_sort Kaka, Ubedullah
collection UPM
description This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly (
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spelling upm.eprints-468472018-01-31T06:57:24Z http://psasir.upm.edu.my/id/eprint/46847/ Validation of a modified algometer to measure nociceptive thresholds in awake dogs Kaka, Ubedullah Hui, Cheng Chen Yong, Meng Goh Abdul Abubakar, Adamu Fakurazi, Sharida Ebrahimi, Mahdi This study was conducted to validate the use of a modified algometer device to measure mechanical nociceptive thresholds in six dogs. Dogs were administered morphine intravenously (IV) at 1 mg/kg or saline at equivolume in a crossover design with one-week washout period. Mechanical nociceptive thresholds were determined before, after the administration of treatments at 5 minutes, and hourly for 8 hours. Thresholds were recorded at the carpal pad, metacarpal foot pad, tibia, femur, and abdomen. Heart rates, body temperature, and respiration were recorded at similar time points. Thresholds increased significantly ( Hindawi Publishing Corporation 2015 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf Kaka, Ubedullah and Hui, Cheng Chen and Yong, Meng Goh and Abdul Abubakar, Adamu and Fakurazi, Sharida and Ebrahimi, Mahdi (2015) Validation of a modified algometer to measure nociceptive thresholds in awake dogs. BioMed Research International. art. no. 375421. pp. 1-7. ISSN 2314-6133; ESSN: 2314-6141 10.1155/2015/375421
spellingShingle Kaka, Ubedullah
Hui, Cheng Chen
Yong, Meng Goh
Abdul Abubakar, Adamu
Fakurazi, Sharida
Ebrahimi, Mahdi
Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title_full Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title_fullStr Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title_full_unstemmed Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title_short Validation of a modified algometer to measure nociceptive thresholds in awake dogs
title_sort validation of a modified algometer to measure nociceptive thresholds in awake dogs
url http://psasir.upm.edu.my/id/eprint/46847/1/Validation%20of%20a%20modified%20algometer%20to%20measure%20nociceptive%20thresholds%20in%20awake%20dogs.pdf
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