An overview on germinated brown rice and its nutrigenomic implications

White rice is a major staple food for people in low to middle income countries and it can increase the risk of cardiometabolic disease. Brown rice, especially when germinated, is a healthier alternative. Various functional properties have been documented for the bioactive-rich germinated brown rice....

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Main Authors: Imam, Mustapha Umar, Ismail, Maznah
Other Authors: Bagchi, Debasis
Format: Book Section
Language:English
Published: John Wiley & Sons 2015
Online Access:http://psasir.upm.edu.my/id/eprint/47303/1/An%20overview%20on%20germinated%20brown%20rice%20and%20its%20nutrigenomic%20implications.pdf
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author Imam, Mustapha Umar
Ismail, Maznah
author2 Bagchi, Debasis
author_facet Bagchi, Debasis
Imam, Mustapha Umar
Ismail, Maznah
author_sort Imam, Mustapha Umar
collection UPM
description White rice is a major staple food for people in low to middle income countries and it can increase the risk of cardiometabolic disease. Brown rice, especially when germinated, is a healthier alternative. Various functional properties have been documented for the bioactive-rich germinated brown rice. Nutrigenomic studies, dwelling on interactions at diet-genome interface, have expanded our understanding of the role of diets on health. The nutrigenomic basis for the functional properties of GBR have also been reported; its antihyperglycemic, hypocholesterolemic, and antioxidative effects are mediated by its bioactives, partly via transcriptional regulation of genes involved in gluconeogenesis, cholesterol metabolism, and oxidative stress, respectively. Additionally, GBR's ability to improve menopausal symptoms is reported to be due to its ability to upregulate bone metabolism and uterine estrogen related genes, and downregulate inflammatory genes. Food synergy plays a role in the overall functional effects of GBR. Further studies on proteomics, metabolomics, nutrikinetics, and nutridynamics are indicated.
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spelling upm.eprints-473032021-09-04T10:16:04Z http://psasir.upm.edu.my/id/eprint/47303/ An overview on germinated brown rice and its nutrigenomic implications Imam, Mustapha Umar Ismail, Maznah White rice is a major staple food for people in low to middle income countries and it can increase the risk of cardiometabolic disease. Brown rice, especially when germinated, is a healthier alternative. Various functional properties have been documented for the bioactive-rich germinated brown rice. Nutrigenomic studies, dwelling on interactions at diet-genome interface, have expanded our understanding of the role of diets on health. The nutrigenomic basis for the functional properties of GBR have also been reported; its antihyperglycemic, hypocholesterolemic, and antioxidative effects are mediated by its bioactives, partly via transcriptional regulation of genes involved in gluconeogenesis, cholesterol metabolism, and oxidative stress, respectively. Additionally, GBR's ability to improve menopausal symptoms is reported to be due to its ability to upregulate bone metabolism and uterine estrogen related genes, and downregulate inflammatory genes. Food synergy plays a role in the overall functional effects of GBR. Further studies on proteomics, metabolomics, nutrikinetics, and nutridynamics are indicated. John Wiley & Sons Bagchi, Debasis Swaroop, Anand Bagchi, Manashi 2015 Book Section PeerReviewed text en http://psasir.upm.edu.my/id/eprint/47303/1/An%20overview%20on%20germinated%20brown%20rice%20and%20its%20nutrigenomic%20implications.pdf Imam, Mustapha Umar and Ismail, Maznah (2015) An overview on germinated brown rice and its nutrigenomic implications. In: Genomics, Proteomics and Metabolomics in Nutraceuticals and Functional Foods. John Wiley & Sons, Chichester, United Kingdom, pp. 504-517. ISBN 9781118930427; EISBN: 9781118930458 https://onlinelibrary.wiley.com/doi/pdf/10.1002/9781118930458.ch39 10.1002/9781118930458.ch39
spellingShingle Imam, Mustapha Umar
Ismail, Maznah
An overview on germinated brown rice and its nutrigenomic implications
title An overview on germinated brown rice and its nutrigenomic implications
title_full An overview on germinated brown rice and its nutrigenomic implications
title_fullStr An overview on germinated brown rice and its nutrigenomic implications
title_full_unstemmed An overview on germinated brown rice and its nutrigenomic implications
title_short An overview on germinated brown rice and its nutrigenomic implications
title_sort overview on germinated brown rice and its nutrigenomic implications
url http://psasir.upm.edu.my/id/eprint/47303/1/An%20overview%20on%20germinated%20brown%20rice%20and%20its%20nutrigenomic%20implications.pdf
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