Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem

Two active compounds, andrographolide and neoandrographolide were extracted from Andrographis paniculata planted under rubber ecosystem and analysed using isocratic HPLC (High Performance Liquid Chromatography) system. Quantity of andrographolide and neoandrographolide from the methanol extract of t...

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Main Authors: Mat Ali, Mohd Shukri, Mirad, Razali, Shaari, Khozirah, Yunus, Norlia, Mohamed Tamin, Mohamed Senawi, Ismail, Abdul Ghani
Format: Article
Language:English
Published: Malaysian Agricultural Research and Development Institute (MARDI) 2005
Online Access:http://psasir.upm.edu.my/id/eprint/48942/1/Determination%20of%20andrographolide%20and%20neoandrographolide%20levels%20in%20hempedu%20bumi%20%28Andrographis%20paniculata%20Nees%29%20grown%20under%20rubber%20ecosystem.pdf
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author Mat Ali, Mohd Shukri
Mirad, Razali
Shaari, Khozirah
Yunus, Norlia
Mohamed Tamin, Mohamed Senawi
Ismail, Abdul Ghani
author_facet Mat Ali, Mohd Shukri
Mirad, Razali
Shaari, Khozirah
Yunus, Norlia
Mohamed Tamin, Mohamed Senawi
Ismail, Abdul Ghani
author_sort Mat Ali, Mohd Shukri
collection UPM
description Two active compounds, andrographolide and neoandrographolide were extracted from Andrographis paniculata planted under rubber ecosystem and analysed using isocratic HPLC (High Performance Liquid Chromatography) system. Quantity of andrographolide and neoandrographolide from the methanol extract of the samples grown under rubber were compared to the extracts from the sample grown by monocropping method in Serdang which was taken as control. Andrographolide (ADGP) level of A. paniculata grown under rubber was slightly lower (9.40%) compared to the control (23.23%). However, neoandrographolide (NADGP) from A. paniculata grown under rubber was higher (19.83%) compared to the extract of A. paniculata from the control (11.13%). The differences could be due to the biochemical pathway of the compounds influenced by the environment, which has some effect on the synthesis of secondary or tertiary metabolites in the plant.
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spelling upm.eprints-489422016-12-30T02:25:55Z http://psasir.upm.edu.my/id/eprint/48942/ Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem Mat Ali, Mohd Shukri Mirad, Razali Shaari, Khozirah Yunus, Norlia Mohamed Tamin, Mohamed Senawi Ismail, Abdul Ghani Two active compounds, andrographolide and neoandrographolide were extracted from Andrographis paniculata planted under rubber ecosystem and analysed using isocratic HPLC (High Performance Liquid Chromatography) system. Quantity of andrographolide and neoandrographolide from the methanol extract of the samples grown under rubber were compared to the extracts from the sample grown by monocropping method in Serdang which was taken as control. Andrographolide (ADGP) level of A. paniculata grown under rubber was slightly lower (9.40%) compared to the control (23.23%). However, neoandrographolide (NADGP) from A. paniculata grown under rubber was higher (19.83%) compared to the extract of A. paniculata from the control (11.13%). The differences could be due to the biochemical pathway of the compounds influenced by the environment, which has some effect on the synthesis of secondary or tertiary metabolites in the plant. Malaysian Agricultural Research and Development Institute (MARDI) 2005 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/48942/1/Determination%20of%20andrographolide%20and%20neoandrographolide%20levels%20in%20hempedu%20bumi%20%28Andrographis%20paniculata%20Nees%29%20grown%20under%20rubber%20ecosystem.pdf Mat Ali, Mohd Shukri and Mirad, Razali and Shaari, Khozirah and Yunus, Norlia and Mohamed Tamin, Mohamed Senawi and Ismail, Abdul Ghani (2005) Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem. Journal of Tropical Agriculture and Food Science, 33 (2). pp. 303-309. ISSN 1394-9829; ESSN: 2289-9650 http://ejtafs.mardi.gov.my/index.php/publication/issues/archive/69-2005/volume-33-no2/296-330201
spellingShingle Mat Ali, Mohd Shukri
Mirad, Razali
Shaari, Khozirah
Yunus, Norlia
Mohamed Tamin, Mohamed Senawi
Ismail, Abdul Ghani
Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title_full Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title_fullStr Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title_full_unstemmed Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title_short Determination of andrographolide and neoandrographolide levels in hempedu bumi (Andrographis paniculata Nees) grown under rubber ecosystem
title_sort determination of andrographolide and neoandrographolide levels in hempedu bumi andrographis paniculata nees grown under rubber ecosystem
url http://psasir.upm.edu.my/id/eprint/48942/1/Determination%20of%20andrographolide%20and%20neoandrographolide%20levels%20in%20hempedu%20bumi%20%28Andrographis%20paniculata%20Nees%29%20grown%20under%20rubber%20ecosystem.pdf
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