Survival of GRAS base formulated vaccine against environmental stress and storage durability
Current study explores the rigidity and endurance of GRAS base formulated vaccine against environmental stress exposed during process of formulation, packaging and its release into desired pathway and environment. Evaluation were conducted from initial step in vaccine formulation, freeze drying proc...
| Main Authors: | , , , , |
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| Formato: | Conference or Workshop Item |
| Idioma: | English |
| Publicado: |
2012
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| Acceso en liña: | http://psasir.upm.edu.my/id/eprint/50226/1/2-7.pdf |
| _version_ | 1825930291142721536 |
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| author | Shamsudin, Mariana Nor Idrus, E. S. Abdul Rahim, R. Idris, N. H. Mohd Alipiah, N. F. |
| author_facet | Shamsudin, Mariana Nor Idrus, E. S. Abdul Rahim, R. Idris, N. H. Mohd Alipiah, N. F. |
| author_sort | Shamsudin, Mariana Nor |
| collection | UPM |
| description | Current study explores the rigidity and endurance of GRAS base formulated vaccine against environmental stress exposed during process of formulation, packaging and its release into desired pathway and environment. Evaluation were conducted from initial step in vaccine formulation, freeze drying process preservation, storage endurance, packaging environment until exposure into gut environment. Experiment were designed to suit bile condition of fish stomach to ensure viability of vaccine after passing through the fish intestine and time taken for the vaccine to be release and circulated in the bloodstream. Salinity reading tested ranged between 5ppm – 35ppm and pH reading recorded for test ranged between pH2 (acidic bile condition) to pH10 (alkaline). Experiments were conducted for the duration of 24 months for shelf life storage. |
| first_indexed | 2024-03-06T09:09:21Z |
| format | Conference or Workshop Item |
| id | upm.eprints-50226 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:09:21Z |
| publishDate | 2012 |
| record_format | dspace |
| spelling | upm.eprints-502262017-02-02T05:00:54Z http://psasir.upm.edu.my/id/eprint/50226/ Survival of GRAS base formulated vaccine against environmental stress and storage durability Shamsudin, Mariana Nor Idrus, E. S. Abdul Rahim, R. Idris, N. H. Mohd Alipiah, N. F. Current study explores the rigidity and endurance of GRAS base formulated vaccine against environmental stress exposed during process of formulation, packaging and its release into desired pathway and environment. Evaluation were conducted from initial step in vaccine formulation, freeze drying process preservation, storage endurance, packaging environment until exposure into gut environment. Experiment were designed to suit bile condition of fish stomach to ensure viability of vaccine after passing through the fish intestine and time taken for the vaccine to be release and circulated in the bloodstream. Salinity reading tested ranged between 5ppm – 35ppm and pH reading recorded for test ranged between pH2 (acidic bile condition) to pH10 (alkaline). Experiments were conducted for the duration of 24 months for shelf life storage. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50226/1/2-7.pdf Shamsudin, Mariana Nor and Idrus, E. S. and Abdul Rahim, R. and Idris, N. H. and Mohd Alipiah, N. F. (2012) Survival of GRAS base formulated vaccine against environmental stress and storage durability. In: International Conference on One Health and 24th VAM Congress 2012, 21-23 Sept. 2012, Marriott Putrajaya. (pp. 321-323). |
| spellingShingle | Shamsudin, Mariana Nor Idrus, E. S. Abdul Rahim, R. Idris, N. H. Mohd Alipiah, N. F. Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title | Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title_full | Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title_fullStr | Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title_full_unstemmed | Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title_short | Survival of GRAS base formulated vaccine against environmental stress and storage durability |
| title_sort | survival of gras base formulated vaccine against environmental stress and storage durability |
| url | http://psasir.upm.edu.my/id/eprint/50226/1/2-7.pdf |
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