Free radical scavenging activity of Syzygium polyanthum leaves

There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino...

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Main Authors: Yassir, M. A., Abdul Kadir, Arifah, Ismail, Amin, Othman, Fauziah
Format: Conference or Workshop Item
Language:English
Published: 2012
Online Access:http://psasir.upm.edu.my/id/eprint/50247/1/2-19.pdf
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author Yassir, M. A.
Abdul Kadir, Arifah
Ismail, Amin
Othman, Fauziah
author_facet Yassir, M. A.
Abdul Kadir, Arifah
Ismail, Amin
Othman, Fauziah
author_sort Yassir, M. A.
collection UPM
description There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino-bis-3-ethylbenzothiazoline-6-sulfonic Acid (ABTS) radical by using an ELISA reader technique. The results showed that SP directly reacted and quenched ABTS free radicals in the system. The IC50 value of SP was significantly (P <0.05) more effective than that of ascorbic acid, and quenched significantly (P <0.05) more ABTS radicals at low concentrations (5 and 10 μg/mL) than that of ascorbic acid. Moreover, the total antioxidant capacity (TAC) of SP was also significantly (P <0.05) higher than that of ascorbic acid under same experimental condition. In conclusion, the results of ABTS assay reveal potent antioxidant and free radical scavenging activity of SP higher than that of standard ascorbic acid which may serve as a new natural antioxidant.
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spelling upm.eprints-502472017-03-01T09:38:54Z http://psasir.upm.edu.my/id/eprint/50247/ Free radical scavenging activity of Syzygium polyanthum leaves Yassir, M. A. Abdul Kadir, Arifah Ismail, Amin Othman, Fauziah There is a growing interest in the usage of antioxidants in attempt to prevent oxidative damage caused by free radicals in the human body. This study was undertaken to determine the free radical scavenging activity of methanolic extract of Syzygium polyanthum (SP) leaves against the stable 2,2-Azino-bis-3-ethylbenzothiazoline-6-sulfonic Acid (ABTS) radical by using an ELISA reader technique. The results showed that SP directly reacted and quenched ABTS free radicals in the system. The IC50 value of SP was significantly (P <0.05) more effective than that of ascorbic acid, and quenched significantly (P <0.05) more ABTS radicals at low concentrations (5 and 10 μg/mL) than that of ascorbic acid. Moreover, the total antioxidant capacity (TAC) of SP was also significantly (P <0.05) higher than that of ascorbic acid under same experimental condition. In conclusion, the results of ABTS assay reveal potent antioxidant and free radical scavenging activity of SP higher than that of standard ascorbic acid which may serve as a new natural antioxidant. 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50247/1/2-19.pdf Yassir, M. A. and Abdul Kadir, Arifah and Ismail, Amin and Othman, Fauziah (2012) Free radical scavenging activity of Syzygium polyanthum leaves. In: International Conference on One Health and 24th VAM Congress 2012, 21-23 Sept. 2012, Marriott Putrajaya. (pp. 399-401).
spellingShingle Yassir, M. A.
Abdul Kadir, Arifah
Ismail, Amin
Othman, Fauziah
Free radical scavenging activity of Syzygium polyanthum leaves
title Free radical scavenging activity of Syzygium polyanthum leaves
title_full Free radical scavenging activity of Syzygium polyanthum leaves
title_fullStr Free radical scavenging activity of Syzygium polyanthum leaves
title_full_unstemmed Free radical scavenging activity of Syzygium polyanthum leaves
title_short Free radical scavenging activity of Syzygium polyanthum leaves
title_sort free radical scavenging activity of syzygium polyanthum leaves
url http://psasir.upm.edu.my/id/eprint/50247/1/2-19.pdf
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