Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets

The influence of particle size upon surface roughness and wall friction of Labisia pumila powder extracts during tablet compaction was studied. Labisia pumila is a popular Malaysian herb known for the treatment of postpartum mothers, gonorrhoea, rheumatism, pile and bone diseases. Powder materials a...

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Main Authors: Etti, Christopher Joseph, Yusof, Yus Aniza, Chin, Nyuk Ling, Aziz, Mohammad Gulzarul
Format: Conference or Workshop Item
Language:English
Published: Faculty of Engineering, Universiti Putra Malaysia 2012
Online Access:http://psasir.upm.edu.my/id/eprint/50673/1/_TechnicalPapers_CAFEi2012_121.pdf
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author Etti, Christopher Joseph
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
author_facet Etti, Christopher Joseph
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
author_sort Etti, Christopher Joseph
collection UPM
description The influence of particle size upon surface roughness and wall friction of Labisia pumila powder extracts during tablet compaction was studied. Labisia pumila is a popular Malaysian herb known for the treatment of postpartum mothers, gonorrhoea, rheumatism, pile and bone diseases. Powder materials are known for tablets formation suitable for usage as oral dosage when subjected to mechanical forces. These tablets are known to be influenced by friction between powder particles, and the wall of compacting vessel. A universal testing machine with forces ranging from 5.0 to 10.0 kN ± 0.1kN with a compression speed of 5 mm min-1 was used to compact the herb using a 13- mm- diameter cylindrical stainless steel uniaxial die. During compression, tablet strength was directly proportional to compaction pressure and inversely proportional to particle size. The surface roughness of Labisia pumila compacted tablets increased with increase in particle size of powder extract, and the bottom surfaces of tablets were rougher than the upper surfaces. The tablet strength increased with a decrease in wall friction. From the compaction models, 0.4g of powder was most compressible and easiest to deform into tablets compared with 0.6g and 0.8g of powders upon uniform loads. Generally, particle size and wall friction are seen to influence the surface roughness and tablets strength.
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spelling upm.eprints-506732017-03-02T06:18:39Z http://psasir.upm.edu.my/id/eprint/50673/ Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets Etti, Christopher Joseph Yusof, Yus Aniza Chin, Nyuk Ling Aziz, Mohammad Gulzarul The influence of particle size upon surface roughness and wall friction of Labisia pumila powder extracts during tablet compaction was studied. Labisia pumila is a popular Malaysian herb known for the treatment of postpartum mothers, gonorrhoea, rheumatism, pile and bone diseases. Powder materials are known for tablets formation suitable for usage as oral dosage when subjected to mechanical forces. These tablets are known to be influenced by friction between powder particles, and the wall of compacting vessel. A universal testing machine with forces ranging from 5.0 to 10.0 kN ± 0.1kN with a compression speed of 5 mm min-1 was used to compact the herb using a 13- mm- diameter cylindrical stainless steel uniaxial die. During compression, tablet strength was directly proportional to compaction pressure and inversely proportional to particle size. The surface roughness of Labisia pumila compacted tablets increased with increase in particle size of powder extract, and the bottom surfaces of tablets were rougher than the upper surfaces. The tablet strength increased with a decrease in wall friction. From the compaction models, 0.4g of powder was most compressible and easiest to deform into tablets compared with 0.6g and 0.8g of powders upon uniform loads. Generally, particle size and wall friction are seen to influence the surface roughness and tablets strength. Faculty of Engineering, Universiti Putra Malaysia 2012 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/50673/1/_TechnicalPapers_CAFEi2012_121.pdf Etti, Christopher Joseph and Yusof, Yus Aniza and Chin, Nyuk Ling and Aziz, Mohammad Gulzarul (2012) Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets. In: International Conference on Agricultural and Food Engineering for Life (Cafei2012), 26-28 Nov. 2012, Palm Garden Hotel, Putrajaya. (pp. 350-359). http://cafei.upm.edu.my/download.php?filename=/TechnicalPapers/CAFEi2012_121.pdf
spellingShingle Etti, Christopher Joseph
Yusof, Yus Aniza
Chin, Nyuk Ling
Aziz, Mohammad Gulzarul
Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title_full Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title_fullStr Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title_full_unstemmed Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title_short Effects of particle size upon surface roughness and wall friction during compaction of Labisia pumila tablets
title_sort effects of particle size upon surface roughness and wall friction during compaction of labisia pumila tablets
url http://psasir.upm.edu.my/id/eprint/50673/1/_TechnicalPapers_CAFEi2012_121.pdf
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AT chinnyukling effectsofparticlesizeuponsurfaceroughnessandwallfrictionduringcompactionoflabisiapumilatablets
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