Bioassay-guided isolation of deoxypodophyllotoxin, the cytotoxic constituent of Juniperus chinensis
The ethanol extract from the leaves of Juniperus chinensis was found to be cytotoxic towards HeLa cells. Bioassay-guided fractionation of the EtOAc soluble faction directed by the microtitration cytotoxic assay revealed that the cytotoxic compound was deoxypodophyllotoxin. All the tumour cell lines...
Main Authors: | Ali, Abdul Manaf, Ismail, Intan Safinar, Mohamed Mackeen, Muhammad Mukram, El-Sharkawy, Saleh Hassan, Takahata, Kyoya, Kanzaki, Hiroshi, Kawazu, Kazuyoshi |
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Format: | Article |
Language: | English |
Published: |
Korean Society of Pharmacognosy
1998
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Online Access: | http://psasir.upm.edu.my/id/eprint/51340/1/51340.pdf |
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