Disrupted interferon-related molecular networks and the over-expressed Ifnar1 in the brain of adult Ts1Cje mouse model of Down syndrome
Down syndrome (DS) is a chromosomal disorder resulting from trisomy of human chromosome 21 (HSA21) and all DS individual exhibit cognitive impairment. Ts1Cje mouse model of DS has a triplicated region of mouse chromosome 16 (MMU16) which is homologous to HSA21. Three interferon receptor genes (Ifnar...
Main Authors: | Tan, Kai Leng, Lee, Han Chung, Ling, King Hwa, Scott, Hamish. S., Lai, Mei I., Vidyadaran, Sharmili, Cheah, Pike See |
---|---|
Format: | Conference or Workshop Item |
Language: | English |
Published: |
2016
|
Online Access: | http://psasir.upm.edu.my/id/eprint/53953/1/Disrupted%20interferon-related%20molecular%20networks%20and%20the%20over-expressed%20Ifnar1%20in%20the%20brain%20of%20adult%20Ts1Cje%20mouse%20model%20of%20Down%20syndrome.pdf |
Similar Items
-
Overexpression of interferon alpha or beta receptors in the brain of adult Ts1Cje mouse model of Down syndrome
by: Tan, Kai Leng, et al.
Published: (2015) -
Functional transcriptome analysis of the postnatal brain of the Ts1Cje mouse model for Down syndrome reveals global disruption of interferon-related molecular networks
by: Ling, King Hwa, et al.
Published: (2014) -
Ts1Cje mouse model for Down syndrome research
by: Ling, King Hwa
Published: (2015) -
Gene network disruptions and neurogenesis defects in the adult Ts1Cje mouse model of Down syndrome
by: Hewitt, Chelsee Ann, et al.
Published: (2010) -
The role of JAK-STAT signalling in the developing brain of Ts1Cje mouse model for Down syndrome
by: Lee, Han Chung, et al.
Published: (2015)