Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds
Endocrine disrupting compounds (EDCs) have been widely reported as potential carcinogenic threats to the human population. The release of EDCs to environmental compartments, such as water, sediment, and biota, has been monitored extensively. Considering the typically low levels of EDC concentrations...
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| Format: | Article |
| Language: | English |
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Elsevier
2016
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| Online Access: | http://psasir.upm.edu.my/id/eprint/54154/1/Endocrine%20disrupting%20compounds%20.pdf |
| _version_ | 1825930982853705728 |
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| author | Tuan Omar, Tuan Fauzan Ahmad, Azrilawani Aris, Ahmad Zaharin Md Yusoff, Fatimah |
| author_facet | Tuan Omar, Tuan Fauzan Ahmad, Azrilawani Aris, Ahmad Zaharin Md Yusoff, Fatimah |
| author_sort | Tuan Omar, Tuan Fauzan |
| collection | UPM |
| description | Endocrine disrupting compounds (EDCs) have been widely reported as potential carcinogenic threats to the human population. The release of EDCs to environmental compartments, such as water, sediment, and biota, has been monitored extensively. Considering the typically low levels of EDC concentrations found in environmental samples and the complexity of biota matrices, the main challenge is with the extraction and cleanup of samples, as well as with finding a sensitive enough instrumentation system for analyte detection. This paper presents a review of recent trends in the analysis of EDCs in environmental matrices. The focus of this review is three classes of environmentally important EDCs; namely, pharmaceuticals, estrogenic hormones, and alkylphenol compounds. Discussions about state-of-the-art instrumentation and sample preparation techniques, as well as a review of sample storage and preservation, are highlighted. Overall, the use of LC-MS-MS as an instrumentation technique has increased over the past 15 years. |
| first_indexed | 2024-03-06T09:19:50Z |
| format | Article |
| id | upm.eprints-54154 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:19:50Z |
| publishDate | 2016 |
| publisher | Elsevier |
| record_format | dspace |
| spelling | upm.eprints-541542018-03-01T07:07:48Z http://psasir.upm.edu.my/id/eprint/54154/ Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds Tuan Omar, Tuan Fauzan Ahmad, Azrilawani Aris, Ahmad Zaharin Md Yusoff, Fatimah Endocrine disrupting compounds (EDCs) have been widely reported as potential carcinogenic threats to the human population. The release of EDCs to environmental compartments, such as water, sediment, and biota, has been monitored extensively. Considering the typically low levels of EDC concentrations found in environmental samples and the complexity of biota matrices, the main challenge is with the extraction and cleanup of samples, as well as with finding a sensitive enough instrumentation system for analyte detection. This paper presents a review of recent trends in the analysis of EDCs in environmental matrices. The focus of this review is three classes of environmentally important EDCs; namely, pharmaceuticals, estrogenic hormones, and alkylphenol compounds. Discussions about state-of-the-art instrumentation and sample preparation techniques, as well as a review of sample storage and preservation, are highlighted. Overall, the use of LC-MS-MS as an instrumentation technique has increased over the past 15 years. Elsevier 2016-12 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/54154/1/Endocrine%20disrupting%20compounds%20.pdf Tuan Omar, Tuan Fauzan and Ahmad, Azrilawani and Aris, Ahmad Zaharin and Md Yusoff, Fatimah (2016) Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds. Trends in Analytical Chemistry, 85 (pt. C). pp. 241-259. ISSN 0165-9936 https://www.sciencedirect.com/science/article/pii/S0165993616300917 Endocrine disrupting compounds (EDCs); Pharmaceuticals; Estrogenic hormones; Alkylphenol; Environmental matrices; Biota; Sample preservation 10.1016/j.trac.2016.08.004 |
| spellingShingle | Endocrine disrupting compounds (EDCs); Pharmaceuticals; Estrogenic hormones; Alkylphenol; Environmental matrices; Biota; Sample preservation Tuan Omar, Tuan Fauzan Ahmad, Azrilawani Aris, Ahmad Zaharin Md Yusoff, Fatimah Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title | Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title_full | Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title_fullStr | Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title_full_unstemmed | Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title_short | Endocrine disrupting compounds (EDCs) in environmental matrices: review of analytical strategies for pharmaceuticals, estrogenic hormones, and alkylphenol compounds |
| title_sort | endocrine disrupting compounds edcs in environmental matrices review of analytical strategies for pharmaceuticals estrogenic hormones and alkylphenol compounds |
| topic | Endocrine disrupting compounds (EDCs); Pharmaceuticals; Estrogenic hormones; Alkylphenol; Environmental matrices; Biota; Sample preservation |
| url | http://psasir.upm.edu.my/id/eprint/54154/1/Endocrine%20disrupting%20compounds%20.pdf |
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