Fibroblast growth factor receptor 4 (FGF4) and fibroblast growth factor 19 (FGFR19) autocrine enhance brest cancer cells survival

Fibroblast growth factor receptor 4 (FGF4) and fibroblast growth factor 19 (FGFR19) autocrine enhance brest cancer cells survival

Basal-like breast cancer is an aggressive tumor subtype with poor prognosis. The discovery of underlying mechanisms mediating tumor cell survival, and the development of novel agents to target these pathways, is a priority for patients with basal-like breast cancer. From a functional screen to ident...

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Bibliographic Details
Main Authors: Tiong, Kai Hung, Tan, Boon Shing, Choo, Heng Lungh, Chung, Felicia Fei-Lei, Hii, Ling Wei, Tan, Si Hoey, Khor, Nelson Tze Woei, Wong, Shew Fung, See, Sze Jia, Tan, Yuen Fen, Rosli, Rozita, Cheong, Soon Keng, Leong, Chee Onn
Format: Article
Language:English
Published: Impact Journals LLC 2016
Subjects:
Fibroblast growth factor; Breast cancer; RNAi screen; FGFR4; FGF19
Online Access:http://psasir.upm.edu.my/id/eprint/54313/1/Fibroblast%20growth%20factor%20%20receptor%204.pdf

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