Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria
Fingerroot (Boesenbergia rotunda) is a medicinal and culinary herb in the ginger family (Zingiberaceae). It has been used for beauty and skin treatment, however, antibacterial activity of B. rotunda extract against acne-causing bacteria has not been investigated. The aim of this study is to analyse...
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| Médium: | Článek |
| Jazyk: | English |
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RJPBCS
2016
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| On-line přístup: | http://psasir.upm.edu.my/id/eprint/55073/1/Antibacterial%20activity%20of%20fingerroot%20%28Boesenbergia%20rotunda%29%20extract%20against%20acne-.pdf |
| _version_ | 1825931149229162496 |
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| author | Rahman, Mohd Azuar Hamizan Lau, Kah Yan Rukayadi, Yaya |
| author_facet | Rahman, Mohd Azuar Hamizan Lau, Kah Yan Rukayadi, Yaya |
| author_sort | Rahman, Mohd Azuar Hamizan |
| collection | UPM |
| description | Fingerroot (Boesenbergia rotunda) is a medicinal and culinary herb in the ginger family (Zingiberaceae). It has been used for beauty and skin treatment, however, antibacterial activity of B. rotunda extract against acne-causing bacteria has not been investigated. The aim of this study is to analyse the antibacterial activity of B. rotunda extract acne-inducing bacteria; Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. The methanolic extract of B. rotunda was tested for antimicrobial activity against acne-causing bacteria in term of disk diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and kill-time curve using the standard methods of Clinical and Laboratory Standard Institute (CLSI). The B. rotunda extract has inhibited the growth of P. acnes ATCC6919, P. acnes clinical strain, S. epidermidis KCCM40003 and S. aureus KCCM12255 with MIC value of 0.63-, 0.63-, 0.31-, and 0.02 mg/mL, respectively. Moreover, MBC of B. rotunda extract was 1.25-, 1.25-, 0.63-, and 0.04 mg/mL on P. acnes ATCC6919, P. acnes clinical strain, S. epidermidis KCCM40003 and S. aureus KCCM12255, respectively. Time-kill curves analyses demonstrated that the bactericidal endpoint of B. rotunda extract on P. acnes ATCC6919, P. acnes clinical strain, and S. aureus KCCM12255 was 4× MIC after 4 h of incubation. Meanwhile, endpoint of B. rotunda extract on S. epidermidis was killed at 8×MIC after 0.5 h of incubation. The result show that B. rotunda extract have potent antibacterial activity against acne-inducing bacteria. |
| first_indexed | 2024-03-06T09:22:21Z |
| format | Article |
| id | upm.eprints-55073 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:22:21Z |
| publishDate | 2016 |
| publisher | RJPBCS |
| record_format | dspace |
| spelling | upm.eprints-550732018-08-13T07:47:56Z http://psasir.upm.edu.my/id/eprint/55073/ Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria Rahman, Mohd Azuar Hamizan Lau, Kah Yan Rukayadi, Yaya Fingerroot (Boesenbergia rotunda) is a medicinal and culinary herb in the ginger family (Zingiberaceae). It has been used for beauty and skin treatment, however, antibacterial activity of B. rotunda extract against acne-causing bacteria has not been investigated. The aim of this study is to analyse the antibacterial activity of B. rotunda extract acne-inducing bacteria; Propionibacterium acnes, Staphylococcus aureus, and Staphylococcus epidermidis. The methanolic extract of B. rotunda was tested for antimicrobial activity against acne-causing bacteria in term of disk diffusion, minimum inhibitory concentration (MIC), minimum bactericidal concentration (MBC) and kill-time curve using the standard methods of Clinical and Laboratory Standard Institute (CLSI). The B. rotunda extract has inhibited the growth of P. acnes ATCC6919, P. acnes clinical strain, S. epidermidis KCCM40003 and S. aureus KCCM12255 with MIC value of 0.63-, 0.63-, 0.31-, and 0.02 mg/mL, respectively. Moreover, MBC of B. rotunda extract was 1.25-, 1.25-, 0.63-, and 0.04 mg/mL on P. acnes ATCC6919, P. acnes clinical strain, S. epidermidis KCCM40003 and S. aureus KCCM12255, respectively. Time-kill curves analyses demonstrated that the bactericidal endpoint of B. rotunda extract on P. acnes ATCC6919, P. acnes clinical strain, and S. aureus KCCM12255 was 4× MIC after 4 h of incubation. Meanwhile, endpoint of B. rotunda extract on S. epidermidis was killed at 8×MIC after 0.5 h of incubation. The result show that B. rotunda extract have potent antibacterial activity against acne-inducing bacteria. RJPBCS 2016-11 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/55073/1/Antibacterial%20activity%20of%20fingerroot%20%28Boesenbergia%20rotunda%29%20extract%20against%20acne-.pdf Rahman, Mohd Azuar Hamizan and Lau, Kah Yan and Rukayadi, Yaya (2016) Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria. Research Journal of Pharmaceutical, Biological and Chemical Sciences, 7 (6). pp. 2157-2163. ISSN 0975-8585 https://www.rjpbcs.com/pdf/2016_7(6)/[294].pdf |
| spellingShingle | Rahman, Mohd Azuar Hamizan Lau, Kah Yan Rukayadi, Yaya Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title | Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title_full | Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title_fullStr | Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title_full_unstemmed | Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title_short | Antibacterial activity of fingerroot (Boesenbergia rotunda) extract against acne-inducing bacteria |
| title_sort | antibacterial activity of fingerroot boesenbergia rotunda extract against acne inducing bacteria |
| url | http://psasir.upm.edu.my/id/eprint/55073/1/Antibacterial%20activity%20of%20fingerroot%20%28Boesenbergia%20rotunda%29%20extract%20against%20acne-.pdf |
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