Antimicrobial stewardship program in a Malaysian district hospital: first year experience
Backgrounds & Objective: Antimicrobial resistance is an alarming public health threat that requires urgent global solution. Implementation of antimicrobial stewardship program (ASP) is an essential practice element for healthcare institutions in gate-keeping judicious antimicrobial use. This stu...
| Main Authors: | , , , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Professional Medical Publications
2016
|
| Online Access: | http://psasir.upm.edu.my/id/eprint/55086/1/Antimicrobial%20stewardship%20program%20in%20a%20Malaysian%20district%20hospital%20first%20year%20experience.pdf |
| _version_ | 1825931151854796800 |
|---|---|
| author | Yap, Diana Fui Sing Yang, Liang Boo Mukhlis, Roshalina Pek, Woon Chin Fan, Kee Hoo |
| author_facet | Yap, Diana Fui Sing Yang, Liang Boo Mukhlis, Roshalina Pek, Woon Chin Fan, Kee Hoo |
| author_sort | Yap, Diana Fui Sing |
| collection | UPM |
| description | Backgrounds & Objective: Antimicrobial resistance is an alarming public health threat that requires urgent global solution. Implementation of antimicrobial stewardship program (ASP) is an essential practice element for healthcare institutions in gate-keeping judicious antimicrobial use. This study highlighted the development, first year experience, and result of the implementation of ASP utilizing persuasive and restrictive approaches in a Malaysian district hospital.
Methods: An observational study was conducted between January 2015 to December 2015 on implementation of ASP among hospitalized inpatients age 12 years old and above.
Results: Recommendations were provided for 60% of cases (110 patients) with the average acceptance rate of 83.33%. Majority of the interventions were to stop the antimicrobial therapy (30.3%), and the most common audited antimicrobials was Piperacillin/ Tazobactam (25.5%), followed by Meropenem (11.82%), Amoxicillin/Clavulanate and Vancomycin (8.18%) respectively. The concordance rate towards authorization policy was increased in 2015 (71.59% of cases) as compared before the implementation of ASP in 2014 (60.6% of cases). Restrictive enforcement under ASP had been shown to improve significantly adherence rate towards antimicrobials authorization policy (p-value: 0.004).
Conclusion: ASP was successfully implemented in a district hospital. Future studies on its clinical outcomes are important to evaluate its effectiveness as well as focus on the improvement to the pre-existing strategies and measures. |
| first_indexed | 2024-03-06T09:22:24Z |
| format | Article |
| id | upm.eprints-55086 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:22:24Z |
| publishDate | 2016 |
| publisher | Professional Medical Publications |
| record_format | dspace |
| spelling | upm.eprints-550862017-12-29T05:46:51Z http://psasir.upm.edu.my/id/eprint/55086/ Antimicrobial stewardship program in a Malaysian district hospital: first year experience Yap, Diana Fui Sing Yang, Liang Boo Mukhlis, Roshalina Pek, Woon Chin Fan, Kee Hoo Backgrounds & Objective: Antimicrobial resistance is an alarming public health threat that requires urgent global solution. Implementation of antimicrobial stewardship program (ASP) is an essential practice element for healthcare institutions in gate-keeping judicious antimicrobial use. This study highlighted the development, first year experience, and result of the implementation of ASP utilizing persuasive and restrictive approaches in a Malaysian district hospital. Methods: An observational study was conducted between January 2015 to December 2015 on implementation of ASP among hospitalized inpatients age 12 years old and above. Results: Recommendations were provided for 60% of cases (110 patients) with the average acceptance rate of 83.33%. Majority of the interventions were to stop the antimicrobial therapy (30.3%), and the most common audited antimicrobials was Piperacillin/ Tazobactam (25.5%), followed by Meropenem (11.82%), Amoxicillin/Clavulanate and Vancomycin (8.18%) respectively. The concordance rate towards authorization policy was increased in 2015 (71.59% of cases) as compared before the implementation of ASP in 2014 (60.6% of cases). Restrictive enforcement under ASP had been shown to improve significantly adherence rate towards antimicrobials authorization policy (p-value: 0.004). Conclusion: ASP was successfully implemented in a district hospital. Future studies on its clinical outcomes are important to evaluate its effectiveness as well as focus on the improvement to the pre-existing strategies and measures. Professional Medical Publications 2016 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/55086/1/Antimicrobial%20stewardship%20program%20in%20a%20Malaysian%20district%20hospital%20first%20year%20experience.pdf Yap, Diana Fui Sing and Yang, Liang Boo and Mukhlis, Roshalina and Pek, Woon Chin and Fan, Kee Hoo (2016) Antimicrobial stewardship program in a Malaysian district hospital: first year experience. Pakistan Journal of Medical Sciences, 32 (4). pp. 999-1004. ISSN 1682-024X; ESSN: 1681-715X http://www.pjms.com.pk/ 10.12669/pjms.324.9855 |
| spellingShingle | Yap, Diana Fui Sing Yang, Liang Boo Mukhlis, Roshalina Pek, Woon Chin Fan, Kee Hoo Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title | Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title_full | Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title_fullStr | Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title_full_unstemmed | Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title_short | Antimicrobial stewardship program in a Malaysian district hospital: first year experience |
| title_sort | antimicrobial stewardship program in a malaysian district hospital first year experience |
| url | http://psasir.upm.edu.my/id/eprint/55086/1/Antimicrobial%20stewardship%20program%20in%20a%20Malaysian%20district%20hospital%20first%20year%20experience.pdf |
| work_keys_str_mv | AT yapdianafuising antimicrobialstewardshipprograminamalaysiandistricthospitalfirstyearexperience AT yangliangboo antimicrobialstewardshipprograminamalaysiandistricthospitalfirstyearexperience AT mukhlisroshalina antimicrobialstewardshipprograminamalaysiandistricthospitalfirstyearexperience AT pekwoonchin antimicrobialstewardshipprograminamalaysiandistricthospitalfirstyearexperience AT fankeehoo antimicrobialstewardshipprograminamalaysiandistricthospitalfirstyearexperience |