Effects of small molecule inhibitors targeting PI3K, EGFR, IGF-1R, MTOR, SMAD3 and MEK in tube formation and 3-D spheroid assay
Angiogenesis is the process where new blood capillaries are formed from the preexisting blood vessels. The MEK/ERK and PI3K/Akt signaling pathways are involved in the processes that drive cancer progression such as cell motility, metastasis and angiogenesis. The cellular events in angiogenesis which...
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| Format: | Thesis |
| Language: | English |
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2014
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| Online Access: | http://psasir.upm.edu.my/id/eprint/55642/1/FPSK%28m%29%202014%2051RR.pdf |