Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits
The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic...
| Main Authors: | , , , |
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| Format: | Conference or Workshop Item |
| Language: | English |
| Published: |
AIP Publishing LLC
2013
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| Online Access: | http://psasir.upm.edu.my/id/eprint/57634/1/Therapeutic%20activity%20of%20crude%20ethanolic%20extract%20of%20Artemisia%20herba%20alba%20against%20Trypanosoma%20evansi%20in%20rabbits.pdf |
| _version_ | 1825931650926641152 |
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| author | Awad, Fathy Mohamed Ali Abu Hasan, Zainal Abidin Osman, Abdinasir Yusuf Ibrahim, Nazlina |
| author_facet | Awad, Fathy Mohamed Ali Abu Hasan, Zainal Abidin Osman, Abdinasir Yusuf Ibrahim, Nazlina |
| author_sort | Awad, Fathy Mohamed Ali |
| collection | UPM |
| description | The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic extract (CEE) compared to those from the negative control group. Similarly, there was also haematologically significant difference (p<0.05) where low mean levels of packed cell volume (PCV) was observed in Groups 1-4 respectively. In contrast, there was no statistically significant difference in almost all investigated parameters between positive control and treatment groups of animals. In conclusion, both CEE of A. herba-alba and Berenil® showed relatively a parasitaemia and normal haematological values in infected rabbits, thereby confirming their antiparasitic properties. |
| first_indexed | 2024-03-06T09:29:59Z |
| format | Conference or Workshop Item |
| id | upm.eprints-57634 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:29:59Z |
| publishDate | 2013 |
| publisher | AIP Publishing LLC |
| record_format | dspace |
| spelling | upm.eprints-576342017-10-24T08:20:27Z http://psasir.upm.edu.my/id/eprint/57634/ Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits Awad, Fathy Mohamed Ali Abu Hasan, Zainal Abidin Osman, Abdinasir Yusuf Ibrahim, Nazlina The present work was conducted to evaluate the antitrypanosomal efficacy of crude ethanolic extract (CEE) of the aerial parts of Artemisia herba alba against Trypanosoma evansi infection in an animal model. The results indicated low levels of parasitaemia in rabbits administered with crude ethanolic extract (CEE) compared to those from the negative control group. Similarly, there was also haematologically significant difference (p<0.05) where low mean levels of packed cell volume (PCV) was observed in Groups 1-4 respectively. In contrast, there was no statistically significant difference in almost all investigated parameters between positive control and treatment groups of animals. In conclusion, both CEE of A. herba-alba and Berenil® showed relatively a parasitaemia and normal haematological values in infected rabbits, thereby confirming their antiparasitic properties. AIP Publishing LLC 2013 Conference or Workshop Item PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/57634/1/Therapeutic%20activity%20of%20crude%20ethanolic%20extract%20of%20Artemisia%20herba%20alba%20against%20Trypanosoma%20evansi%20in%20rabbits.pdf Awad, Fathy Mohamed Ali and Abu Hasan, Zainal Abidin and Osman, Abdinasir Yusuf and Ibrahim, Nazlina (2013) Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits. In: 2013 UKM FST Postgraduate Colloquium, 3-4 July 2013, Faculty of Science and Technology, Universiti Kebangsaan Malaysia. (pp. 177-179). 10.1063/1.4858650 |
| spellingShingle | Awad, Fathy Mohamed Ali Abu Hasan, Zainal Abidin Osman, Abdinasir Yusuf Ibrahim, Nazlina Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title | Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title_full | Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title_fullStr | Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title_full_unstemmed | Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title_short | Therapeutic activity of crude ethanolic extract of Artemisia herba alba against Trypanosoma evansi in rabbits |
| title_sort | therapeutic activity of crude ethanolic extract of artemisia herba alba against trypanosoma evansi in rabbits |
| url | http://psasir.upm.edu.my/id/eprint/57634/1/Therapeutic%20activity%20of%20crude%20ethanolic%20extract%20of%20Artemisia%20herba%20alba%20against%20Trypanosoma%20evansi%20in%20rabbits.pdf |
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