Benzylidene derivatives of andrographolide inhibit growth of breast and colon cancer cells in vitro by inducing G1 arrest and apoptosis
Background and purpose: Andrographolide, the major phytoconstituent of Andrographis paniculata, was previously shown by us to have activity against breast cancer. This led to synthesis of new andrographolide analogues to find compounds with better activity than the parent compound. Selected benzylid...
Main Authors: | Jada, Srinivasa Rao, Matthews, Charlie, Saad, Mohd Said, Hamzah, Ahmad Sazali, Lajis, Md Nordin, Stevens, M. F. G., Stanslas, J. |
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Format: | Article |
Language: | English English |
Published: |
Macmillan Publishers Limited
2008
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Online Access: | http://psasir.upm.edu.my/id/eprint/5784/1/Benzylidene%20derivatives%20of%20andrographolide%20inhibit%20growth%20of%20breast%20and%20colon%20cancer%20cells%20in%20vitro%20by%20inducing%20G1%20arrest%20and%20apoptosis.pdf |
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