An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia

Introduction: Microbial keratitis (MK) is an important cause for corneal blindness and understanding its risk factors enable us to improve management and minimise its complications. Methods: In this retrospective case review, medical records of all patients treated for MK from 2006 to 2013 was analy...

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Main Authors: Omar, Nazri, Abdul Muna'aim, Maimunah, Md. Saleh, Rafidah, Mohd Kasim, Zaidah, Mohd Isa, Muhammad
Format: Article
Language:English
Published: Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2017
Online Access:http://psasir.upm.edu.my/id/eprint/58283/1/2017082916074706_MJMHS_Vol13_No2_2017_-_0019_-_5th_proof.pdf
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author Omar, Nazri
Abdul Muna'aim, Maimunah
Md. Saleh, Rafidah
Mohd Kasim, Zaidah
Mohd Isa, Muhammad
author_facet Omar, Nazri
Abdul Muna'aim, Maimunah
Md. Saleh, Rafidah
Mohd Kasim, Zaidah
Mohd Isa, Muhammad
author_sort Omar, Nazri
collection UPM
description Introduction: Microbial keratitis (MK) is an important cause for corneal blindness and understanding its risk factors enable us to improve management and minimise its complications. Methods: In this retrospective case review, medical records of all patients treated for MK from 2006 to 2013 was analysed to know the socio-demography, preceding risk factors, clinical characteristics, causative organisms and final visual outcome. Results: A total of 174 patients (180 eyes) were included in this study. Identifiable ocular risk factors included contact lens (CL) usage (85, 47.2%), ocular trauma (50, 27.8%), ocular surface disease (21, 11.6%), steroid use (6, 3.3%) and immuno-compromy (19, 10.5%). Association factors for presenting uncorrected visual acuity (UCVA) were age group (p=0.013), size (p<0.001), location (p<0.001) and hypopyon (p<0.001). The predictors for final best spectacle-corrected visual acuity (BSCVA) were age group (p<0.001), nationality (p=0.020), occupation (p<0.001), CL use (p<0.001), ocular surface disease (p=0.048), size (p<0.001) and location (p<0.044), hospitalisation duration (p=0.002) and presenting UCVA (p<0.001). Conclusions: Contact lens was the most frequent predisposing risk factor for microbial keratitis, followed by ocular trauma. Understanding the association factors for presenting vision and predictors for final vision may help in the patients’ management and improve eventual outcome of microbial keratitis.
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spelling upm.eprints-582832018-01-26T09:43:39Z http://psasir.upm.edu.my/id/eprint/58283/ An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia Omar, Nazri Abdul Muna'aim, Maimunah Md. Saleh, Rafidah Mohd Kasim, Zaidah Mohd Isa, Muhammad Introduction: Microbial keratitis (MK) is an important cause for corneal blindness and understanding its risk factors enable us to improve management and minimise its complications. Methods: In this retrospective case review, medical records of all patients treated for MK from 2006 to 2013 was analysed to know the socio-demography, preceding risk factors, clinical characteristics, causative organisms and final visual outcome. Results: A total of 174 patients (180 eyes) were included in this study. Identifiable ocular risk factors included contact lens (CL) usage (85, 47.2%), ocular trauma (50, 27.8%), ocular surface disease (21, 11.6%), steroid use (6, 3.3%) and immuno-compromy (19, 10.5%). Association factors for presenting uncorrected visual acuity (UCVA) were age group (p=0.013), size (p<0.001), location (p<0.001) and hypopyon (p<0.001). The predictors for final best spectacle-corrected visual acuity (BSCVA) were age group (p<0.001), nationality (p=0.020), occupation (p<0.001), CL use (p<0.001), ocular surface disease (p=0.048), size (p<0.001) and location (p<0.044), hospitalisation duration (p=0.002) and presenting UCVA (p<0.001). Conclusions: Contact lens was the most frequent predisposing risk factor for microbial keratitis, followed by ocular trauma. Understanding the association factors for presenting vision and predictors for final vision may help in the patients’ management and improve eventual outcome of microbial keratitis. Faculty of Medicine and Health Sciences, Universiti Putra Malaysia 2017 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/58283/1/2017082916074706_MJMHS_Vol13_No2_2017_-_0019_-_5th_proof.pdf Omar, Nazri and Abdul Muna'aim, Maimunah and Md. Saleh, Rafidah and Mohd Kasim, Zaidah and Mohd Isa, Muhammad (2017) An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia. Malaysian Journal of Medicine and Health Sciences, 13 (2). pp. 47-57. ISSN 1675-8544 http://www.medic.upm.edu.my/upload/dokumen/2017082916074706_MJMHS_Vol13_No2_2017_-_0019_-_5th_proof.pdf
spellingShingle Omar, Nazri
Abdul Muna'aim, Maimunah
Md. Saleh, Rafidah
Mohd Kasim, Zaidah
Mohd Isa, Muhammad
An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title_full An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title_fullStr An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title_full_unstemmed An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title_short An 8-year retrospective review of microbial keratitis in a secondary referral centre in Malaysia
title_sort 8 year retrospective review of microbial keratitis in a secondary referral centre in malaysia
url http://psasir.upm.edu.my/id/eprint/58283/1/2017082916074706_MJMHS_Vol13_No2_2017_-_0019_-_5th_proof.pdf
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