Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property
DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular grow...
Main Authors: | , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Malaysian Society for Molecular Biology and Biotechnology
2004
|
Online Access: | http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf |
_version_ | 1825931826947948544 |
---|---|
author | Yiap, Beow Chin Wong, Clemente Michael Vui Ling Mohd Yusuf, Hirzun Abdul Rahim, Raha |
author_facet | Yiap, Beow Chin Wong, Clemente Michael Vui Ling Mohd Yusuf, Hirzun Abdul Rahim, Raha |
author_sort | Yiap, Beow Chin |
collection | UPM |
description | DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular growth and budding pattern. The yeast cells carrying an additional copy of DSN1 gene have an increased growth rate and they formed a highly retarded multiple bud complex. These phenomena suggest possible growth stimulating property of the gene product. |
first_indexed | 2024-03-06T09:32:38Z |
format | Article |
id | upm.eprints-58522 |
institution | Universiti Putra Malaysia |
language | English |
last_indexed | 2024-03-06T09:32:38Z |
publishDate | 2004 |
publisher | Malaysian Society for Molecular Biology and Biotechnology |
record_format | dspace |
spelling | upm.eprints-585222018-01-22T02:07:52Z http://psasir.upm.edu.my/id/eprint/58522/ Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property Yiap, Beow Chin Wong, Clemente Michael Vui Ling Mohd Yusuf, Hirzun Abdul Rahim, Raha DSN1 is a spindle pole body component that functions in the chromosomal segregation process of yeast. The effect of additional DSN1 gene dosage on the yeast cell has yet to be established. The work from this study indicated that an extra gene dosage of DSN1 caused abnormalities in both cellular growth and budding pattern. The yeast cells carrying an additional copy of DSN1 gene have an increased growth rate and they formed a highly retarded multiple bud complex. These phenomena suggest possible growth stimulating property of the gene product. Malaysian Society for Molecular Biology and Biotechnology 2004 Article PeerReviewed application/pdf en http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf Yiap, Beow Chin and Wong, Clemente Michael Vui Ling and Mohd Yusuf, Hirzun and Abdul Rahim, Raha (2004) Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property. Asia Pacific Journal of Molecular Biology and Biotechnology, 12 (1&2). pp. 43-47. ISSN 0128-7451 http://www.msmbb.org.my/apjmbb/html12/12g.htm |
spellingShingle | Yiap, Beow Chin Wong, Clemente Michael Vui Ling Mohd Yusuf, Hirzun Abdul Rahim, Raha Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title | Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title_full | Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title_fullStr | Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title_full_unstemmed | Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title_short | Extra dose of Dsn1p (Yir010wp) expressed from episomal plasmid in normal Saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern, suggesting its growth stimulating property |
title_sort | extra dose of dsn1p yir010wp expressed from episomal plasmid in normal saccharomyces cerevisiae diploid wild type has augmented growth rate and altered budding pattern suggesting its growth stimulating property |
url | http://psasir.upm.edu.my/id/eprint/58522/1/Extra%20dose%20of%20Dsn1p%20%28Yir010wp%29%20expressed%20from%20episomal%20plasmid%20in%20normal%20Saccharomyces%20cerevisiae%20diploid.pdf |
work_keys_str_mv | AT yiapbeowchin extradoseofdsn1pyir010wpexpressedfromepisomalplasmidinnormalsaccharomycescerevisiaediploidwildtypehasaugmentedgrowthrateandalteredbuddingpatternsuggestingitsgrowthstimulatingproperty AT wongclementemichaelvuiling extradoseofdsn1pyir010wpexpressedfromepisomalplasmidinnormalsaccharomycescerevisiaediploidwildtypehasaugmentedgrowthrateandalteredbuddingpatternsuggestingitsgrowthstimulatingproperty AT mohdyusufhirzun extradoseofdsn1pyir010wpexpressedfromepisomalplasmidinnormalsaccharomycescerevisiaediploidwildtypehasaugmentedgrowthrateandalteredbuddingpatternsuggestingitsgrowthstimulatingproperty AT abdulrahimraha extradoseofdsn1pyir010wpexpressedfromepisomalplasmidinnormalsaccharomycescerevisiaediploidwildtypehasaugmentedgrowthrateandalteredbuddingpatternsuggestingitsgrowthstimulatingproperty |