Halophenol Rearrangement in Lewis Acid-Catalyzed Friedel–Crafts Conditions: Evidence of Competitive Initial Protonation and Acylation
Halogen rearrangement was observed during the Lewis acid-catalyzed Friedel–Crafts reaction of phthalic anhydride with bromophenols or bromoanisole. Further investigation revealed that 2-, 3-, and 4-bromophenols undergo rearrangement into other isomers under these reaction conditions. Product distrib...
Main Authors: | Koushik, Saha, Lajis, Md Nordin, Abas, Faridah, Ali Naji, Nabil, Hamzah, A. Sazali, Shaari, Khozirah |
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Format: | Article |
Language: | English English |
Published: |
CSIRO Publishing
2008
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Online Access: | http://psasir.upm.edu.my/id/eprint/6021/1/Halophenol%20Rearrangement%20in%20Lewis%20Acid.pdf |
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