A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes
Zerumbone (ZER) is a phytochemical isolated from the subtropical Zingiberaceae family and as a natural compound it has different biomedical properties such as antioxidant, anti-inflammatory anti-proliferative activity. ZER also has effects on angiogenesis and acts as an antitumor drug in the treatme...
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| Format: | Article |
| Language: | English |
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MDPI
2017
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| Online Access: | http://psasir.upm.edu.my/id/eprint/60713/1/A%20review%20of%20the%20biomedical%20applications%20of%20zerumbone%20and%20the%20techniques%20for%20its%20extraction%20from%20ginger%20rhizomes.pdf |
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| author | Kalantari, Katayoon Moniri, Mona Moghaddam, Amin Boroumand Abdul Rahim, Raha Ariff, Arbakariya Izadiyan, Zahra Mohamad, Rosfarizan |
| author_facet | Kalantari, Katayoon Moniri, Mona Moghaddam, Amin Boroumand Abdul Rahim, Raha Ariff, Arbakariya Izadiyan, Zahra Mohamad, Rosfarizan |
| author_sort | Kalantari, Katayoon |
| collection | UPM |
| description | Zerumbone (ZER) is a phytochemical isolated from the subtropical Zingiberaceae family and as a natural compound it has different biomedical properties such as antioxidant, anti-inflammatory anti-proliferative activity. ZER also has effects on angiogenesis and acts as an antitumor drug in the treatment of cancer, showing selective toxicity toward various cancer cell lines. Several techniques also have been established for extraction of ZER from the rhizomes of ginger. This review paper is an overview of recent research about different extraction methods and their efficiencies, in vivo and vitro investigations of ZER and also its prominent chemopreventive properties and treatment mechanisms. Most of the studies mentioned in this review paper may be useful use as a knowledge summary to explain ZER extraction and anticancer activities, which will show a way for the development of strategies in the treatment of malignancies using ZER. |
| first_indexed | 2024-03-06T09:38:49Z |
| format | Article |
| id | upm.eprints-60713 |
| institution | Universiti Putra Malaysia |
| language | English |
| last_indexed | 2024-03-06T09:38:49Z |
| publishDate | 2017 |
| publisher | MDPI |
| record_format | dspace |
| spelling | upm.eprints-607132019-04-02T02:00:40Z http://psasir.upm.edu.my/id/eprint/60713/ A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes Kalantari, Katayoon Moniri, Mona Moghaddam, Amin Boroumand Abdul Rahim, Raha Ariff, Arbakariya Izadiyan, Zahra Mohamad, Rosfarizan Zerumbone (ZER) is a phytochemical isolated from the subtropical Zingiberaceae family and as a natural compound it has different biomedical properties such as antioxidant, anti-inflammatory anti-proliferative activity. ZER also has effects on angiogenesis and acts as an antitumor drug in the treatment of cancer, showing selective toxicity toward various cancer cell lines. Several techniques also have been established for extraction of ZER from the rhizomes of ginger. This review paper is an overview of recent research about different extraction methods and their efficiencies, in vivo and vitro investigations of ZER and also its prominent chemopreventive properties and treatment mechanisms. Most of the studies mentioned in this review paper may be useful use as a knowledge summary to explain ZER extraction and anticancer activities, which will show a way for the development of strategies in the treatment of malignancies using ZER. MDPI 2017 Article PeerReviewed text en http://psasir.upm.edu.my/id/eprint/60713/1/A%20review%20of%20the%20biomedical%20applications%20of%20zerumbone%20and%20the%20techniques%20for%20its%20extraction%20from%20ginger%20rhizomes.pdf Kalantari, Katayoon and Moniri, Mona and Moghaddam, Amin Boroumand and Abdul Rahim, Raha and Ariff, Arbakariya and Izadiyan, Zahra and Mohamad, Rosfarizan (2017) A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes. Molecules, 22 (10). art. no. 1645. pp. 1-24. ISSN 1431-5157; ESSN: 1420-3049 https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6151537/pdf/molecules-22-01645.pdf 10.3390/molecules22101645 |
| spellingShingle | Kalantari, Katayoon Moniri, Mona Moghaddam, Amin Boroumand Abdul Rahim, Raha Ariff, Arbakariya Izadiyan, Zahra Mohamad, Rosfarizan A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title | A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title_full | A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title_fullStr | A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title_full_unstemmed | A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title_short | A review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| title_sort | review of the biomedical applications of zerumbone and the techniques for its extraction from ginger rhizomes |
| url | http://psasir.upm.edu.my/id/eprint/60713/1/A%20review%20of%20the%20biomedical%20applications%20of%20zerumbone%20and%20the%20techniques%20for%20its%20extraction%20from%20ginger%20rhizomes.pdf |
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